Spinifex may refer to:
- Spinifex (genus), a genus of grass which is indigenous to the coastal areas of Australasia and Indonesia
- Triodia (plant genus), a hummock grass of arid Australia, covering twenty percent of the Australian continent (although not technically Spinifex, it is commonly referred to as such)
- Spinifex hopping mouse, a mouse native to the central and western Australian arid zones
- Spinifex people, or Pila Nguru, an Australian tribe named after the grass
- Spinifex, a texture in certain ultramafic lavas such as komatiite
- Spinifex Pigeon (Geophaps plumifera), a bird found in Australia
- Spinifex Ridge, a mine in Australia
- Spinifexbird (Eremiornis carteri), a bird found in Australia
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