digplanet beta 1: Athena
Share digplanet:

Agriculture

Applied sciences

Arts

Belief

Business

Chronology

Culture

Education

Environment

Geography

Health

History

Humanities

Language

Law

Life

Mathematics

Nature

People

Politics

Science

Society

Technology

"E301" redirects here. For the Japanese train, see EV-E301 series.
Sodium L-ascorbate[1]
Sodium ascorbate.png
Sodium ascorbate powder.jpg
Names
IUPAC name
Sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate
Other names
Sodascorbate; Monosodium ascorbate; E301
Identifiers
134-03-2 YesY
ChEMBL ChEMBL591665 N
EC Number 205-126-1
Jmol interactive 3D Image
PubChem 23667548
RTECS number CI7671000
UNII S033EH8359 N
Properties
C6H7NaO6
Molar mass 198.11 g·mol−1
Appearance minute white to yellow crystals
Odor odorless
Melting point 218 °C (424 °F; 491 K) (decomposes)
62 g/100 mL (25 °C)
78 g/100 mL (75 °C)
Solubility very slightly soluble in alcohol
insoluble in chloroform, ether
Hazards
NFPA 704
Flammability code 0: Will not burn. E.g., water Health code 0: Exposure under fire conditions would offer no hazard beyond that of ordinary combustible material. E.g., sodium chloride Reactivity code 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g., liquid nitrogen Special hazards (white): no codeNFPA 704 four-colored diamond
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Sodium ascorbate is one of a number of mineral salts of ascorbic acid (vitamin C). The molecular formula of this chemical compound is C6H7NaO6. As the sodium salt of ascorbic acid, it is known as a mineral ascorbate. It has not been demonstrated to be more bioavailable than any other form of vitamin C supplement.[2]

Sodium ascorbate normally provides 131 mg of sodium per 1,000 mg of ascorbic acid (1,000 mg of sodium ascorbate contains 889 mg of ascorbic acid and 111 mg of sodium).

As a food additive, it has the E number E301 and is used as an antioxidant and an acidity regulator. It is approved for use as a food additive in the EU,[3] USA,[4] and Australia and New Zealand.[5]

In in vitro studies, sodium ascorbate has been found to produce cytotoxic effects in various malignant cell lines, which include melanoma cells that are particularly susceptible.[6][7]

Production[edit]

Sodium ascorbate is produced by dissolving ascorbic acid in water and adding an equivalent amount of sodium bicarbonate in water. After cessation of effervescence, the sodium ascorbate is precipitated by the addition of isopropanol.

References[edit]

  1. ^ (+)-Sodium L-ascorbate at Sigma-Aldrich
  2. ^ Linus Pauling Institute, Oregon Stare University: "Bioavailability of Different Forms of Vitamin C". Retrieved 2013-09-27. 
  3. ^ UK Food Standards Agency: "Current EU approved additives and their E Numbers". Retrieved 2011-10-27. 
  4. ^ US Food and Drug Administration: "Listing of Food Additives Status Part II". Retrieved 2011-10-27. 
  5. ^ Australia New Zealand Food Standards Code"Standard 1.2.4 - Labelling of ingredients". Retrieved 2011-10-27. 
  6. ^ Chen Q, Espey MG, Krishna MC, Mitchell JB, Corpe CP, Buettner GR, Shacter E, Levine M. (September 2005). "Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a pro-drug to deliver hydrogen peroxide to tissues". Proc Natl Acad Sci U S A. 102 (38): 13604–9. doi:10.1073/pnas.0506390102. PMC 1224653. PMID 16157892. 
  7. ^ Kang JS, Cho D, Kim YI, Hahm E, Kim YS, Jin SN, Kim HN, Kim D, Hur D, Park H, Hwang YI, Lee WJ. . (July 2005). "Sodium ascorbate (vitamin C) induces apoptosis in melanoma cells via the down-regulation of transferrin receptor dependent iron uptake". J Cell Physiol. 204 (1): 192–7. doi:10.1002/jcp.20286. PMID 15672419. 

External links[edit]


Original courtesy of Wikipedia: http://en.wikipedia.org/wiki/Sodium_ascorbate — Please support Wikipedia.
This page uses Creative Commons Licensed content from Wikipedia. A portion of the proceeds from advertising on Digplanet goes to supporting Wikipedia.

226 news items

 
WhaTech
Mon, 18 Jan 2016 17:18:45 -0800

The Global Sodium Ascorbate Industry 2016 Market Research Report is a professional and in-depth study on the current state of the Sodium Ascorbate industry. - Advertisement -. - Premium -. Firstly, the report provides a basic overview of the industry ...
 
WhaTech
Thu, 14 Jan 2016 04:00:00 -0800

The report, 'Global Sodium Ascorbate Market', also contains detailed information on clientele, applications and contact information. Accurate forecasts by credible experts on critical matters such as production, price, and profit are also found in this ...

Nature.com

Nature.com
Mon, 08 Feb 2016 09:02:58 -0800

Briefly, media or lysates containing alkynyl fucose–tagged glycoproteins were incubated with 1 mM copper sulfate and 2 mM sodium ascorbate in PBS with 0.1 mM azide-biotin and 0.1 mM tris-(benzyltriazolylmethyl)amine for 1 h at room temperature. Clicked ...
 
Press Telegraph (blog)
Fri, 05 Feb 2016 03:29:03 -0800

Sodium Ascorbate and after that after that Ascorbic Acid Indication: Used so that you can treat Sodium Ascorbate and after that after that Ascorbic Acid (Vitamin C (Ascorbic Acid)) deficiency, scurvy, past due wound and after that after that bone ...
 
Inquirer.net (blog)
Sun, 15 Apr 2012 18:13:45 -0700

UPON my return to the USA from a medical mission in Macebebe, Pampanga, I received an email from a reader, who is a practicing physician in Cebu, inquiring about the efficacy and safety of sodium ascorbate, which I know is widely advertised as ...
 
Dove Medical Press
Thu, 17 Dec 2015 17:52:30 -0800

Penetration of PC liposomes was tested ex vivo in whole skin, epidermis, and dermis by means of fluorescein and sodium ascorbate. Histology and Franz diffusion cells were used to monitor the percutaneous absorption. Ultraviolet (UV)-high performance ...

Newsmax

Newsmax
Fri, 09 Oct 2015 05:35:05 -0700

Dr. Klenner developed protocols when anyone came into his office, he gave them a 10,000 mg shot of Sodium Ascorbate typically in the Glutes, THEN he started the diagnostic process to find out exactly what they had. In the meantime, he'd given the ...

Newsmax

Newsmax
Mon, 30 Nov 2015 19:22:16 -0800

Maybe the doctors when pressed to give something could give a 1,000 mg pill of Sodium Ascorbate (Vitamin C) instead and have them take that for ... well, ever, which would help them fight the viral infection AND strengthen their immune system to fight ...
Loading

Oops, we seem to be having trouble contacting Twitter

Support Wikipedia

A portion of the proceeds from advertising on Digplanet goes to supporting Wikipedia. Please add your support for Wikipedia!

Searchlight Group

Digplanet also receives support from Searchlight Group. Visit Searchlight