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"E301" redirects here. For the Japanese train, see EV-E301 series.
Sodium L-ascorbate[1]
Sodium ascorbate.png
Sodium ascorbate powder.jpg
Identifiers
CAS number 134-03-2 YesY
PubChem 23667548
EC number 205-126-1
ChEMBL CHEMBL591665 N
RTECS number CI7671000
Jmol-3D images Image 1
Properties
Molecular formula C6H7NaO6
Molar mass 198.11 g mol−1
Appearance minute white to yellow crystals
Odor odorless
Melting point 218 °C (424 °F; 491 K) (decomposes)
Solubility in water 62 g/100mL (25 °C)
78 g/100 mL (75 °C)
Solubility very slightly soluble in alcohol
insoluble in chloroform, ether
Hazards
NFPA 704
Flammability code 0: Will not burn. E.g., water Health code 0: Exposure under fire conditions would offer no hazard beyond that of ordinary combustible material. E.g., sodium chloride Reactivity code 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g., liquid nitrogen Special hazards (white): no codeNFPA 704 four-colored diamond
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

Sodium ascorbate is one of a number of mineral salts of ascorbic acid (vitamin C). The molecular formula of this chemical compound is C6H7NaO6. As the sodium salt of ascorbic acid, it is known as a mineral ascorbate. It has not been demonstrated to be more bioavailable than any other form of vitamin C supplement.[2]

Sodium ascorbate normally provides 131 mg of sodium per 1,000 mg of ascorbic acid (1,000 mg of sodium ascorbate contains 889 mg of ascorbic acid and 111 mg of sodium).

As a food additive, it has the E number E301 and is used as an antioxidant and an acidity regulator. It is approved for use as a food additive in the EU,[3] USA,[4] and Australia and New Zealand.[5]

In in vitro studies, sodium ascorbate has been found to produce cytotoxic effects in various malignant cell lines, which include melanoma cells that are particularly susceptible.[6][7]

Production[edit]

Sodium ascorbate is produced by dissolving ascorbic acid in water and adding an equivalent amount of sodium bicarbonate in water. After cessation of effervescence, the sodium ascorbate is precipitated by the addition of isopropanol.

References[edit]

  1. ^ (+)-Sodium L-ascorbate at Sigma-Aldrich
  2. ^ Linus Pauling Institute, Oregon Stare University: "Bioavailability of Different Forms of Vitamin C". Retrieved 2013-09-27. 
  3. ^ UK Food Standards Agency: "Current EU approved additives and their E Numbers". Retrieved 2011-10-27. 
  4. ^ US Food and Drug Administration: "Listing of Food Additives Status Part II". Retrieved 2011-10-27. 
  5. ^ Australia New Zealand Food Standards Code"Standard 1.2.4 - Labelling of ingredients". Retrieved 2011-10-27. 
  6. ^ Chen Q, Espey MG, Krishna MC, Mitchell JB, Corpe CP, Buettner GR, Shacter E, Levine M. (September 2005). "Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a pro-drug to deliver hydrogen peroxide to tissues". Proc Natl Acad Sci U S A. 102 (38): 13604–9. doi:10.1073/pnas.0506390102. PMC 1224653. PMID 16157892. 
  7. ^ Kang JS, Cho D, Kim YI, Hahm E, Kim YS, Jin SN, Kim HN, Kim D, Hur D, Park H, Hwang YI, Lee WJ. . (July 2005). "Sodium ascorbate (vitamin C) induces apoptosis in melanoma cells via the down-regulation of transferrin receptor dependent iron uptake". J Cell Physiol. 204 (1): 192–7. doi:10.1002/jcp.20286. PMID 15672419. 

External links[edit]


Original courtesy of Wikipedia: http://en.wikipedia.org/wiki/Sodium_ascorbate — Please support Wikipedia.
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Lankaweb
Fri, 24 Oct 2014 11:11:15 -0700

E301 — Sodium ascorbate but not found to cause any problems, E120 — Carmine but it is added to hot dogs. Carmine is another word for the red food dye cochineal, which has no health effects, as long as you are not allergic to insects. Cochineal is ...
 
Food Consumer
Tue, 21 Oct 2014 14:12:38 -0700

Dissolve 25 to 85 grams (25,000-85,000 milligrams) of sodium ascorbate powder in milk and have the patient drink it during the day. Adjust ascorbate dose up or down according to the estimated drug intake. Continued to adjust dose to almost cause loose ...

helpmeoutDOC News - A consistent flow of medical news

helpmeoutDOC News - A consistent flow of medical news
Thu, 09 Oct 2014 02:06:04 -0700

Researchers used Mauer's laboratory to mix different anti-caking agents with powdered sodium ascorbate, a common form of vitamin C, and introduce them to various humidity levels. Sodium ascorbate deliquesces, or dissolves, at 86 percent humidity, but ...

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Wed, 24 Sep 2014 14:45:00 -0700

The researchers then made a standard pork sausage with 20 percent fat—roughly the same content as a commercially prepared sausage—and added glucose, black pepper, and sodium ascorbate, which is used as a pH regulator. Finally, they inoculated the ...

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Thu, 09 Oct 2014 14:45:00 -0700

... kola, ZMapp from tobacco plants, Metallic Nano Particles, Nano Silver, Favipiravir, Lamivudine (Epivir), Brincidofovir, Choloroquine, Crofelemer and Dietary supplements such as Ganoderma, Immunovit, Immunocal, Ascorbic acid and Sodium Ascorbate.

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Wed, 01 Oct 2014 11:45:00 -0700

... the meat produced is ten times cheaper than normal meat. Most hot dogs typically contain, high fructose corn syrup, starch, milk protein, sodium nitrite, flavours, potassium and sodium triphosphates, polyphosphates (E452), sodium ascorbate and carmine.
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