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Punicalagin
Chemical structure of  punicalagin
Names
Other names
2,3-(S)-hexahydroxydiphenoyl-4,6-(S,S)-gallagyl-D-glucose
α-punicalagin
β-punicalagin
Identifiers
65995-63-3 YesY
ChEMBL ChEMBL506814 N
Jmol interactive 3D Image
PubChem 16129869
Properties
C48H28O30
Molar mass 1084.71 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Punicalagin is an ellagitannin, a type of phenolic compounds. It is found in forms alpha and beta in pomegranates (Punica granatum), in Terminalia catappa and Terminalia myriocarpa,[1] and in Combretum molle, the velvet bushwillow, is a plant species found in South Africa.[2] These three genera are all Myrtales and the last two are both Combretaceae.

Health effects[edit]

Punicalagins are the largest molecule found intact in rat plasma after oral ingestion[3] and were found to show no toxic effects in rats who were given a 6% diet of punicalagins for 37 days.[4] Punicalagins are also found to be the major component responsible for pomegranate juice's antioxidant activity.[5]

Punicalagin is water-soluble and has high bioavailability. They are known to hydrolyze into smaller phenolic compounds such as ellagic acid in vivo where one potential mechanism is hydrolysis across the mitochondrial membrane of cultured human colon cells.[6][7]

It is a highly active carbonic anhydrase inhibitor.[8]

References[edit]

  1. ^ Marzouk, M. S. A.; El-Toumy, S. A. A.; Moharram, F. A.; Shalaby, N. M.; Ahmed, A. A. (2002). "Pharmacologically Active Ellagitannins from Terminalia myriocarpa". Planta Medica 68 (6): 523–527. doi:10.1055/s-2002-32549. PMID 12094296. 
  2. ^ Asres, K.; Bucar, F.; Knauder, E.; Yardley, V.; Kendrick, H.; Croft, S. L. (2001). "In vitro antiprotozoal activity of extract and compounds from the stem bark of Combretum molle". Phytotherapy Research 15 (7): 613–617. doi:10.1002/ptr.897. PMID 11746844. 
  3. ^ Cerda et al. Eur J Nutr. 2003 Jan;42(1), pp. 18-28
  4. ^ Cerda et al. J. Agric. Food Chem. 2003, 51, pp. 3493-3501
  5. ^ Gil et al. J Agric Food Chem 2000 48 (10), pp. 4581-4589
  6. ^ Seeram et al. Clin Chim Acta. 2004 Oct;348(1-2), pp. 63-68
  7. ^ Larrosa et al. J Nutr Biochem. 2006 Sep;17(9), pp. 611-625
  8. ^ Satomi, H.; Umemura, K.; Ueno, A.; Hatano, T.; Okuda, T.; Noro, T. (1993). "Carbonic anhydrase inhibitors from the pericarps of Punica granatum L". Biological & Pharmaceutical Bulletin 16 (8): 787–790. doi:10.1248/bpb.16.787. PMID 8220326. 

Original courtesy of Wikipedia: http://en.wikipedia.org/wiki/Punicalagin — Please support Wikipedia.
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193 news items

Latinos Health

Latinos Health
Fri, 05 Feb 2016 02:30:00 -0800

Dr. Fuhrman reports that the compound found in pomegranates called punicalagin has been shown to benefit the heart and blood vessels, and helps lower blood pressure. It also aids in increases the melting of heart blockages. A study has also shown how ...

Thanh Niên

Thanh Niên
Thu, 04 Feb 2016 03:15:00 -0800

Hai chất punicalagin và axit punicic từ hạt lựu là hai loại hợp chất mang lại nhiều lợi ích cho sức khỏe nhất. Punicalagin là chất chống oxy hóa mạnh giúp chống lại các gốc tự do có hại hiệu quả. Axit punicic là một loại axit linoleic liên hợp rất có ...

এনটিভি

এনটিভি
Thu, 04 Feb 2016 20:55:07 -0800

ডালিম অত্যন্ত স্বাস্থ্যকর একটি ফল। এতে আছে আঁশ, প্রোটিন, ভিটামিন-সি, ভিটামিন-কে, ফলেট, পটাশিয়াম ও সুগার। এক কাপ ডালিম থেকে প্রায় ১৪৪ ক্যালরি পাওয়া যায়। ডালিমে রয়েছে পিউনিক্যালাজিন (punicalagin) ও পিউনিসিক এসিড (punicic acid) নামে দুটি স্বাস্থ্যকর ...

Webnoviny.sk

Webnoviny.sk
Tue, 02 Feb 2016 04:22:30 -0800

Granátové jablko obsahuje antioxidant punicalagin, ktorý má priaznivý vplyv na zdravie srdca a krvných ciev. Pravidelná konzumácia tohto ovocia znižuje krvný tlak a znižuje hladinu zlého cholesterolu v tele. 3. Zlepšuje náladu. Ak si chcete zlepšiť ...

Health Liputan6.com

Health Liputan6.com
Mon, 01 Feb 2016 02:35:33 -0800

Tak hanya itu, seperti dikutip Boldsky, Senin (1/2/2016), delima juga memiliki dua antioksidan yang terkandung di dalamnya, yaitu punicalagin dan asam punicic yang berguna untuk mencegah penyakit jantung, kanker, infeksi bakteri dan alzheimer.
 
Dáma.cz
Wed, 20 Jan 2016 22:00:00 -0800

Může za to vitamin C, karotenoidy (ve formě provitaminu A) a punicalagin, jež rozmetají volné radikály na padrť. A nejenom ty. Poslední výzkumy totiž ukázaly, že jeden z nejstarších druhů ovoce na světě je prospěšný proti některým typům škodlivých ...

Yahoo Health

Yahoo Health
Fri, 18 Dec 2015 12:12:24 -0800

Research published in the journal Molecular Nutrition & Food Research in 2014 determined that punicalagin, another compound found in pomegranates, may help slow the progression of Alzheimer's by treating brain inflammation. While the latest finding is ...

ألوان نيوز

ألوان نيوز
Mon, 01 Feb 2016 11:07:30 -0800

الطازج أو المجفف وقشور ثمرة الرمان التي تحتوي علي مواد عفصية (Tannins) بنسبة 20 25% وهو عبارة عن Gall tannins والذي يشمل Granatine, Punicalagin, Punicalin.وقد وجد أن استخدام مسحوق قشر الثمرة إذا مزجت مع العسل النقي يعطي نتائج ايجابية ضد قرحة المعدة ويجب ...
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