digplanet beta 1: Athena
Share digplanet:

Agriculture

Applied sciences

Arts

Belief

Business

Chronology

Culture

Education

Environment

Geography

Health

History

Humanities

Language

Law

Life

Mathematics

Nature

People

Politics

Science

Society

Technology

Punicalagin
Chemical structure of  punicalagin
Names
Other names
2,3-(S)-hexahydroxydiphenoyl-4,6-(S,S)-gallagyl-D-glucose
α-punicalagin
β-punicalagin
Identifiers
65995-63-3 YesY
ChEMBL ChEMBL506814 N
Jmol-3D images Image
PubChem 16129869
Properties
C48H28O30
Molar mass 1084.71 g/mol
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N verify (what isYesY/N?)
Infobox references

Punicalagin is an ellagitannin, a type of phenolic compounds. It is found in forms alpha and beta in pomegranates (Punica granatum), in Terminalia catappa and Terminalia myriocarpa,[1] and in Combretum molle, the velvet bushwillow, is a plant species found in South Africa.[2] These three genera are all Myrtales and the last two are both Combretaceae.

Health effects[edit]

Punicalagins are the largest molecule found intact in rat plasma after oral ingestion[3] and were found to show no toxic effects in rats who were given a 6% diet of punicalagins for 37 days.[4] Punicalagins are also found to be the major component responsible for pomegranate juice's antioxidant activity.[5]

Punicalagin is water soluble and has high bioavailability. They are known to hydrolyze into smaller phenolic compounds such as ellagic acid in vivo where one potential mechanism is hydrolysis across the mitochondrial membrane of cultured human colon cells.[6][7]

It is a highly active carbonic anhydrase inhibitor.[8]

References[edit]

  1. ^ Marzouk, M. S. A.; El-Toumy, S. A. A.; Moharram, F. A.; Shalaby, N. M.; Ahmed, A. A. (2002). "Pharmacologically Active Ellagitannins from Terminalia myriocarpa". Planta Medica 68 (6): 523–527. doi:10.1055/s-2002-32549. PMID 12094296.  edit
  2. ^ Asres, K.; Bucar, F.; Knauder, E.; Yardley, V.; Kendrick, H.; Croft, S. L. (2001). "In vitro antiprotozoal activity of extract and compounds from the stem bark of Combretum molle". Phytotherapy Research 15 (7): 613–617. doi:10.1002/ptr.897. PMID 11746844.  edit
  3. ^ Cerda et al. Eur J Nutr. 2003 Jan;42(1), pp. 18-28
  4. ^ Cerda et al. J. Agric. Food Chem. 2003, 51, pp. 3493-3501
  5. ^ Gil et al. J Agric Food Chem 2000 48 (10), pp. 4581-4589
  6. ^ Seeram et al. Clin Chim Acta. 2004 Oct;348(1-2), pp. 63-68
  7. ^ Larrosa et al. J Nutr Biochem. 2006 Sep;17(9), pp. 611-625
  8. ^ Satomi, H.; Umemura, K.; Ueno, A.; Hatano, T.; Okuda, T.; Noro, T. (1993). "Carbonic anhydrase inhibitors from the pericarps of Punica granatum L". Biological & Pharmaceutical Bulletin 16 (8): 787–790. doi:10.1248/bpb.16.787. PMID 8220326.  edit

Original courtesy of Wikipedia: http://en.wikipedia.org/wiki/Punicalagin — Please support Wikipedia.
This page uses Creative Commons Licensed content from Wikipedia. A portion of the proceeds from advertising on Digplanet goes to supporting Wikipedia.
15 videos foundNext > 

https://youtube.com/devicesupport

Research underway to create pomegranate drug to stem Alzheimer’s and Parkinson’s

Research underway to create pomegranate drug to stem Alzheimer's and Parkinson's - THE onset of Alzheimer's disease can be slowed and some of its symptoms curbed by a natural compound...

Spritzige Drink Idee für den Sommer - perlendes Granatapfel Mineralwasser von einfach Kochen

Besucht uns auf Facebook! http://www.facebook.de/einfachKochen Granatäpfel zeichnen sich durch einen hohen Gehalt bioaktiver Inhaltsstoffe aus. Der Granatapfel enthält größere Mengen Flavonoid.

Pomegranate Concentrate Juice and it's powerful remedies for the cell body

Disclaimer: The information that is shared herein is intended for informational purposes regarding Any advice and/or product(s) mentioned should not be used to diagnose, treat, cure, or prevent...

Portico Quartet - Steepless (DJ Snuk Remix) [PREVIEW]

What do you guys think about the logo? Recently started using Massive and LOVE it! haha But awhile ago I hit a few bugs with it and everything has been a bit of a standstill at the moment....

Granatapfel Extrakt Kapseln - Granatum Plus

http://www.granatumplus.de Kapseln aus Granatapfelextrakt Extrakt Komplex Plus 800 mg Granatum Plus Die Universität Miguel Hernández zertifiziert in ihren analysen, dass jede kapsel Granatum...

The Health Benefits of Pomegranates (Seeds, Juice, etc)

Please like, subscribe, comment and share! SUBSCRIBE: https://www.youtube.com/user/DrJohnKiel FACEBOOK: https://www.facebook.com/medicinelifestyle TWITTER: ...

Mousse au Chocolat weiß einfachKochen weißes Schokoladenmousse Dessert Nachtisch

http://www.einfachkochen.com http://facebook.de/einfachkochen http://www.blog.einfachkochen.com http://astore.amazon.de/einfachkoch02-21 Jetzt kommt der Nachtisch für unser Menü!

Granatapfel als Vorspeise zum Valentinstag Liebesapfel Rezept

http://www.einfachkochen.com http://facebook.de/einfachkochen http://www.blog.einfachkochen.com http://astore.amazon.de/einfachkoch02-21 Valentinstag ist der Tag der Liebenden. Um ein...

Pomegranate Fruit Supports Telomere Health & Length Anti-Aging

http://www.anti-aging-now.com/pomegranate.html -Pomegranate is a very rich source of valuable soluble and insoluble dietary fibers, The most abundant polyphenols in pomegranate juice are the...

15 videos foundNext > 

117 news items

The Raw Food World News

The Raw Food World News
Sun, 24 Aug 2014 17:35:06 -0700

(TRFW News) Recently, pomegranate is getting a lot of attention due to the research of Dr. Dr Olumayokun Olajide's findings that punicalagin, a compound found in pomegranate, could prevent or slow the progression of Alzheimer's Disease. (1).

Western Morning News

Western Morning News
Wed, 08 Apr 2015 07:48:45 -0700

Professor Aviram said: "The pomegranate fruit addresses both the levels of cholesterol and its oxidation rate because it contains both phytosterols (beta sitosterol) , and a most potent antioxidants (punicalagin). Therefore, concentrates of pomegranate ...

Hindustan Times

Hindustan Times
Sat, 04 Apr 2015 09:07:30 -0700

... in UK published in the journal Molecular Nutrition & Food Research in July 2014 has declared that it can prevent Alzheimer's and even slow its onset and progression; all because it has a miraculous antioxidant compound, punicalagin (a polyphenol).
 
Science Daily (press release)
Fri, 22 Aug 2014 08:26:54 -0700

The key breakthrough by Dr Olajide and his co-researchers is to demonstrate that punicalagin, which is a polyphenol – a form of chemical compound – found in pomegranate fruit, can inhibit inflammation in specialised brain cells known as micrologia.

FEMEIA.ro

FEMEIA.ro
Wed, 22 Apr 2015 00:07:30 -0700

În plus, conţine din belşug punicalagin, un polifenol cu rol antioxidant. Sucul de rodie are două mari calităţi: consumat înainte de masă, alungă senzaţia de foame şi o induce pe cea de saţietate, iar băut pur şi simplu, un pahar pe zi, tratează ...

Alzheimer's News Today

Alzheimer's News Today
Mon, 01 Sep 2014 08:34:29 -0700

Punicalagin, the polyphenol chemical compound found in pomegranate, is able to block the inflammation of certain cells of the brain, the micrologia, which are responsible for the deterioration of more brain cells, causing the worsening of Alzheimer's, ...
 
Canon City Daily Record
Tue, 24 Mar 2015 16:15:00 -0700

A compound found only in pomegranates called punicalagin has been shown to benefit the heart and blood vessels. Punicalagin is the major component responsible for pomegranates antioxidant and health benefits. It not only lowers cholesterol, but also ...
 
Science 2.0 (blog)
Wed, 18 Mar 2015 13:36:22 -0700

Reverse aging drugs discovered. (March 2015). "A new class of anti-aging drugs has been identified in a study by a team from The Scripps Research Institute and the Mayo Clinic. In mice, the drugs reduce frailty, improve heart function and extends a ...
Loading

Oops, we seem to be having trouble contacting Twitter

Support Wikipedia

A portion of the proceeds from advertising on Digplanet goes to supporting Wikipedia. Please add your support for Wikipedia!

Searchlight Group

Digplanet also receives support from Searchlight Group. Visit Searchlight