digplanet beta 1: Athena
Share digplanet:


Applied sciences






















Pontine micturition center
NeuroLex ID Barrington's nucleus
Anatomical terms of neuroanatomy

The Pontine micturition center (PMC, also known as Barrington's Nucleus) is a collection of cell bodies located in the rostral pons in the brainstem involved in the supraspinal regulation of micturition (urination). The PMC, when activated, relaxes the urethral sphincter, allowing for urination (micturition). The PMC coordinates with other brain centers, including the medial frontal cortex, insular cortex, hypothalamus and periaqueductal gray (PAG). The PAG in particular acts as a relay station for ascending bladder information from the spinal cord and incoming signals from higher brain areas.


In humans and mammals, neurons in the PMC send descending excitatory projections to spinal parasympathetic preganglionic neurons innervating the bladder and inhibitory interneurons regulating Onuf's nucleus. Additionally, the PMC receives ascending input from the level of the lumbosacral spinal cord. During bladder filling, neurons within the PMC are turned off. However, at a critical level of bladder distention (when one feels the urge to urinate), the afferent activity arising from mechanoreceptors in the bladder wall switches the PMC on and enhances its activity. This activation results in relaxation of the external urethral sphincter and contraction of the bladder due to stimulation of parasympathetic and inhibition of sympathetic outflow to the bladder, and the removal of somatic activation of the male or female external urethral sphincter. This pattern of activity can also be elicited through the conscious desire to void.


  • Fowler CJ, Griffiths D, de Groat WC. (June 9, 2008) "The neural control of micturition." Nature Reviews: Neuroscience (6):453-66
  • Kuipers R, Mouton LJ, Holstege G. (January 1, 2006) "Afferent projections to the pontine micturition center in the cat." The Journal of Comparative Neurology 494(1):36-53
  • Sasaki M. (December 5, 2005) "Role of Barrington's nucleus in micturition". The Journal of Comparative Neurology 5;493(1):21-6

Original courtesy of Wikipedia: http://en.wikipedia.org/wiki/Pontine_micturition_center — Please support Wikipedia.
This page uses Creative Commons Licensed content from Wikipedia. A portion of the proceeds from advertising on Digplanet goes to supporting Wikipedia.
7 videos found


Micturition Reflex - Neural Control of Urination Animation Video.

This video and other urinary system animation (in HD) are available for instant download licensing here: http://www.alilamedicalmedia.com/-/galleries/all-animations/urinary-system-videos Voice...

Harlem Shake (pee pee dance edition)

Customer waiting for the restroom, but he needs to go now! The Harlem shake, originally called the albee, is a dance introduced in 1981 by a Harlem resident named "Al B". The dance was initially...

The Micturition Reflex

I created this animation back in 2004 for Novartis. The animation explains the micturition reflex.

Control Of Respiration

https://www.facebook.com/ArmandoHasudungan Support me: http://www.patreon.com/armando Instagram: http://instagram.com/armandohasudungan Twitter: https://twitter.com/Armando71021105.

Continenza urinaria: il controllo del Sistema Nervoso Centrale (GF Lamberti 1a parte)

Le strutture pontine e ponto mesencefaliche che controllano il meccanismo della minzione e della continenza urinaria. Relazione tenuta al VII Corso di Urologia Funzionale a Verona nel 2013 (1a ...

All About - Human penis (Extended)

What is Human penis? A report all about Human penis for homework/assignment The human penis is an external male sexual organ. It is a reproductive, intromittent organ that additionally...

SPARC Strategic Planning Workshop: Biology & Technology (Day 1)

SPARC Strategic Planning Workshop: Biology & Technology (Day 1) Air date: Wednesday, February 25, 2015, 8:00:00 AM Category: Advisory Board Meetings Runtime: 07:49:26 Description: The...

7 videos found

1 news items

Wed, 18 Feb 2015 09:26:15 -0800

During the storage phase, these superior regions control the pontine micturition center to inhibit voiding. In overactive bladder patients, brain responses are different. Cortical responses become exaggerated, especially in the anterior cingulate ...

Oops, we seem to be having trouble contacting Twitter

Support Wikipedia

A portion of the proceeds from advertising on Digplanet goes to supporting Wikipedia. Please add your support for Wikipedia!

Searchlight Group

Digplanet also receives support from Searchlight Group. Visit Searchlight