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Brain: Obex

Hind-brain of a human embryo of three months—viewed from behind and partly from left side.

Rhomboid fossa.
Latin	Obex
Gray's	subject #187 797
NeuroNames	hier-633

For the protocol, see OBEX.

The obex (from the Latin for barrier) is the point in the human brain at which the fourth ventricle narrows to become the central canal of the spinal cord.

The obex occurs in the caudal medulla.

The decussating of sensory fibers happens at this point.

Clinical significance[edit]

Leisons at the location can result in obstructive hydrocephalus. The most common lesion at this location is a subependymoma, a benign tumor. ^[1]Hemangioblastoma has been observed in this location.^[2] Neurological surgical intervention in the treatment of syringomyelia or hydromyelia may involve plugging the obex to prevent the transmission of cerebrospinal fluid to the central canal of the spinal cord.

References[edit]

^ PMID = 8585504. Hoeffel C, Boukobza M, Polivka M, et al. MR manifestations of subependymomas. AJNR Am J Neuroradiol 1995;16:2121-29.
^ Pavesi G, Berlucchi S, Feletti A, Opocher G, Scienza R (July 2006). "Hemangioblastoma of the obex mimicking anorexia nervosa". Neurology 67 (1): 178–9. doi:10.1212/01.wnl.0000223354.86636.ed. PMID 16832109.

External links[edit]

Photo at aphis.usda.gov (file not found as of 2008-08-16)

This neuroanatomy article is a stub. You can help Wikipedia by expanding it.

Human brain: rhombencephalon, myelencephalon: medulla (TA A14.1.04, GA 9.767)

Dorsal

Surface	Posterior median sulcus · Posterolateral sulcus · Area postrema · Vagal trigone · Hypoglossal trigone · Medial eminence

Grey: Cranial nuclei	afferent: GVA: VII,IX,X: Solitary/tract/Dorsal respiratory group · SVA: Gustatory nucleus · GSA: VIII-v (Lateral, Medial, Inferior) efferent: GSE: XII · GVE: IX,X,XI: Ambiguus · SVE: X: Dorsal · IX: Inferior salivatory nucleus

Grey: other	Gracile nucleus · Cuneate nucleus · Accessory cuneate nucleus

White: Sensory/ascending	Sensory decussation · Medial lemniscus · Inferior cerebellar peduncle (Juxtarestiform body) · Ascending dorsal longitudinal fasciculus · MLF, III, IV and VI

White: Motor/descending	Descending dorsal longitudinal fasciculus · MLF, III, IV and VI

Ventral

White: Motor/descending	Motor decussation · Olivocerebellar tract · Rubro-olivary tract

Grey matter	Ventral respiratory group · Arcuate nucleus of medulla · Inferior olivary nucleus · Rostral ventromedial medulla

Surface	Anterior median fissure · Anterolateral sulcus · Olive · Pyramid

Grey: Raphe/
reticular

Reticular formation (Gigantocellular, Parvocellular, Ventral, Lateral, Paramedian) · Raphe nuclei (Obscurus, Magnus, Pallidus)

M: CNS

anat (n/s/m/p/4/e/b/d/c/a/f/l/g)/phys/devp

noco (m/d/e/h/v/s)/cong/tumr, sysi/epon, injr

proc, drug (N1A/2AB/C/3/4/7A/B/C/D)

Ventricular system, rhombencephalon, met- and myel-: fourth ventricle (TA A14.1.05.701–726, GA 9.797)

Roof (dorsal)

rostral: Superior medullary velum (Frenulum)

caudal: Inferior medullary velum · Taenia of fourth ventricle

Floor/rhomboid fossa (ventral)

rostral (pons): Facial colliculus · Locus coeruleus

caudal (medulla}: Vagal trigone · Hypoglossal trigone · Area postrema · Obex

Medial eminence · Sulcus limitans

Apertures

Median/Magendie · Lateral recess to Lateral/Luschka

Other

Tela chorioidea of fourth ventricle · Fastigium

M: CNS

anat (n/s/m/p/4/e/b/d/c/a/f/l/g)/phys/devp

noco (m/d/e/h/v/s)/cong/tumr, sysi/epon, injr

proc, drug (N1A/2AB/C/3/4/7A/B/C/D)

Original courtesy of Wikipedia: http://en.wikipedia.org/wiki/Obex — Please support Wikipedia.
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Obex

Clinical significance[edit]

References[edit]

External links[edit]

Talk About Obex

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