Non-specific, adsorptive pinocytosis is a form of endocytosis, a process in which small particles are taken in by a cell by splitting off small vesicles from the cell surface. Cationic proteins bind to the negative cell surface and are taken up via the clathrin-mediated system, thus the uptake is intermediate between receptor-mediated endocytosis and non-specific, non-adsorptive pinocytosis. The clathrin-coated pits occupy about 2% of the surface area of the cell and only last about a minute, with an estimated 2500 leaving the average cell surface each minute. The clathrin coats are lost almost immediately, and the membrane is subsequently recycled to the cell surface.
References [edit]
Alberts, Johnson, Lewis, Raff, Roberts, Walter: "Molecular Biology of the Cell", Fourth Edition, Copyright 2002 P.748
See also [edit]
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