Working in a similar manner to a transdermal patch, a metered dose transdermal spray (MDTS) delivers a drug to the surface of the skin which is absorbed into the circulation on a sustained basis. The drug is delivered by a device placed gently against the skin and triggered, causing it to release a light spray containing a proprietary formulation of the drug that quickly dries on the skin to form an invisible drug depot. As it would be from a patch, the drug is then absorbed steadily for a predetermined amount of time.

These methods can be used for symptoms of menopause, female androgen insufficiency, severe pain, central nervous system disorders, male androgen insufficiency, urinary incontinence, contraception and smoking cessation. ^[1]

Notes [edit]

1. ^ Biotechnology.com

v t e Routes of administration / Dosage forms Oral Digestive tract (enteral) Solids Pill Tablet Capsule Time release technology Osmotic delivery system (OROS) Liquids Elixir Emulsion Hydrogel Molecular encapsulation Softgel Solution Suspension Syrup Tincture Tisane Buccal (Sublabial) Sublingual Solids Orally disintegrating tablet (ODT) Film Lollipop Lozenges Chewing gum Liquids Mouthwash Toothpaste Ointment Oral spray Respiratory tract Solids Smoking device Dry powder inhaler (DPI) Liquids Anaesthetic vaporizer Vaporizer Nebulizer metered-dose inhaler (MDI) Gas Oxygen mask Oxygen concentrator Anaesthetic machine Relative analgesia machine Ophthalmic / Otologic / Nasal Nasal spray Ear drops Eye drops Ointment Hydrogel Nanosphere suspension Mucoadhesive microdisc (microsphere tablet) Urogenital Ointment Pessary (vaginal suppository) Vaginal ring Vaginal douche Intrauterine device (IUD) Extra-amniotic infusion Intravesical infusion Rectal (enteral) Ointment Suppository Enema Solution Hydrogel Murphy drip Nutrient enema Dermal Ointment Liniment Paste Film Hydrogel Liposomes Transfersome vesicles Cream Lotion Lip balm Medicated shampoo Dermal patch Transdermal patch Transdermal spray Jet injector Injection / Infusion (into tissue/blood) Skin Intradermal Subcutaneous Transdermal implant Organs Intracavernous Intravitreal Intra-articular injection Transscleral Central nervous system Intracerebral Intrathecal Epidural Circulatory / Musculoskeletal Intravenous Intracardiac Intramuscular Intraosseous Intraperitoneal Nanocell injection Additional explanation: Mucous membranes are used by the human body to absorb the dosage for all routes of administration, except for "Dermal" and "Injection/Infusion". Administration routes can also be grouped as Topical (local effect) or Systemic (defined as Enteral = Digestive tract/Rectal, or Parenteral = All other routes).

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