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A gastrointestinal cocktail, (also known as a GI cocktail or gastric cocktail), is a generic term for a mixture of liquid antacid, viscous lidocaine, and an anticholinergic primarily used to treat dyspepsia. The GI cocktail may also deceptively mask pain originating from the heart.
There is a wide variety of GI cocktail recipes in use today. A very popular one is a mixture of Maalox, viscous lidocaine, and Donnatal, in equal parts. A mixture of 10-30 ml Mylanta, 10 ml Donnatal and 10 ml viscous lidocaine is known as "The Green Goddess," or "Green Lizard." The efficacy of this mixture for the treatment of dyspepsia is generally considered superior to treatment with only any one of its components, due to their varied mechanisms of relief; however, a recent study found that a GI cocktail was no more effective in relieving stomach pain than an antacid alone. The treatment may also provide relief for hiatal hernia patients suffering acute symptoms.
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