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Epithelioid sarcoma
Epithelioid sarcoma - cropped - very high mag.jpg
Micrograph of an epithelioid sarcoma. H&E stain.
Classification and external resources
ICD-O: M8804/3

Epithelioid sarcoma is a rare mesenchymal soft tissue tumour with an epithelioid pattern. It often occurs in the extremities, and is more commonly found in young adults.[1]


The diagnosis is made by examination of tissue, e.g. a biopsy. The diagnosis may be delayed because of the unusual nature of the tumour and its rarity. Its histomorphology near perfectly may mimic an adenocarcinoma, melanoma or granuloma.

Their immunohistochemical profile may mimic those of carcinomas; thus, these tumours may be misdiagnosed as such.

They typically stain for vimentin and keratins. They characteristically have loss of staining for SMARCB1 (INI1, BAF47), and typically stain for CA125.[2]

See also[edit]

Additional images[edit]


  1. ^ Miettinen, M.; Fanburg-Smith, JC.; Virolainen, M.; Shmookler, BM.; Fetsch, JF. (Aug 1999). "Epithelioid sarcoma: an immunohistochemical analysis of 112 classical and variant cases and a discussion of the differential diagnosis.". Hum Pathol 30 (8): 934–42. PMID 10452506. 
  2. ^ Kato H, Hatori M, Kokubun S et al. (March 2004). "CA125 expression in epithelioid sarcoma". Jpn. J. Clin. Oncol. 34 (3): 149–54. doi:10.1093/jjco/hyh027. PMID 15078911. 

External links[edit]

Original courtesy of Wikipedia: http://en.wikipedia.org/wiki/Epithelioid_sarcoma — Please support Wikipedia.
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81 news items

The Guardian

The Guardian
Sat, 28 Feb 2015 17:13:29 -0800

Jessica Ainscough was diagnosed with epithelioid sarcoma seven years ago, a rare soft-tissue cancer which affects young adults and most often first develops in the hand or arm. Doctors suggested Ainscough's best chance of survival would be to have her ...


Wed, 25 Mar 2015 21:18:45 -0700

Some commentators in Australia have noted similarities between Gibson's story and that of the Melbourne woman Jess Ainscough, who died in February of a rare and aggressive form of cancer called epithelioid sarcoma. Ainscough was 22 when diagnosed, ...

MedPage Today

MedPage Today
Tue, 03 Mar 2015 06:45:54 -0800

David Gorski reviews the strange story of Jess Ainscough, a.k.a. the "Wellness Warrior," who died last week after a long and very public and controversial struggle with epithelioid sarcoma. A psychiatrist uses what may or may not be going on with Bruce ...

Scottish Daily Record

Scottish Daily Record
Sat, 14 Mar 2015 05:56:08 -0700

Bryony had been diagnosed with proximal epithelioid sarcoma when she was nine. Despite gruelling chemotherapy and the amputation of an arm, the disease returned a year later. Her aunt Sylvia Marshall said at the time: “Bryony was so brave and fought ...


Thu, 05 Mar 2015 19:22:30 -0800

The Sunshine Coast-based holistic health coach eschewed clinical methods of treatment of her rare cancer, epithelioid sarcoma, in favour of the controversial Gerson therapy, described as a “natural treatment that activates the body's extraordinary ...

Osawatomie Graphic

Osawatomie Graphic
Wed, 11 Mar 2015 06:07:30 -0700

Undiagnosed formally until a few days ago, the aggressive tumor, which is being classified in Ross as a stage 2A epithelioid sarcoma, between the C2 and C3 vertebrae of his spine, is a rare form of cancer that seemingly targets young men between the ...

Rockhampton Morning Bulletin

Rockhampton Morning Bulletin
Wed, 04 Mar 2015 13:11:15 -0800

After being diagnosed with the rare epithelioid sarcoma cancer in 2008, Jess always embraced a positive and proactive attitude to her life and health. Throughout almost seven years with the disease, Jess worked with some of the world's best healers and ...

Herald Sun

Herald Sun
Fri, 13 Mar 2015 03:03:07 -0700

Having been diagnosed at the age of 22 with a rare form of cancer called epithelioid sarcoma, Ainscough embarked on chemotherapy. But as the cancer spread through her left arm and shoulder, she was told the best option was to amputate. “I didn't chop ...

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