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Docosapentaenoic acid designates any straight chain 22:5 fatty acid.


See essential fatty acid#nomenclature for nomenclature.

all-cis-4,7,10,13,16-docosapentaenoic acid (osbond acid)[edit]

The chemical structure of osbond acid showing physiological numbering (red) and chemical numbering (blue) conventions.

all-cis-4,7,10,13,16-docosapentaenoic acid is an ω-6 fatty acid with the trivial name osbond acid. It is formed by an elongation and desaturation of arachidonic acid 20:4 ω-6.

all-cis-7,10,13,16,19-docosapentaenoic acid (clupanodonic acid)[edit]

The chemical structure of clupanodonic acid showing physiological numbering (red) and chemical numbering (blue) conventions.

all-cis-7,10,13,16,19-docosapentaenoic acid is an ω-3 fatty acid with the trivial name clupanodonic acid, commonly called DPA. It is an intermediary between eicosapentaenoic acid (EPA, 20:5 ω-3) and docosahexaenoic acid (DHA, 22:6 ω-3).


Docosapentaenoic acid (DPA) is an omega-3 fatty acid that is structurally similar to eicosapentaenoic acid (EPA) with two more carbon chain units.[1]

Dietary sources

These are the top five sources for DPA according to the USDA Agricultural Research Service: [2]

  1. Fish oil, menhaden .668 22:5 n-3 (DPA) (g) Per Measure
  2. Fish oil, salmon .407 22:5 n-3 (DPA) (g) Per Measure
  3. Salmon, red (sockeye), filets with skin, smoked (Alaska Native) 0.335 22:5 n-3 (DPA) (g) Per Measure
  4. Fish, salmon, Atlantic, farmed, raw .334 22:5 n-3 (DPA) (g) Per Measure
  5. Beef, variety meats and by-products, brain, cooked, simmered 22:5 n-3 (DPA) (g) Per Measure

Seal meat and human breast milk are rich in DPA.[1]


  1. ^ a b Yazdi PG. A review of the biologic and pharmacologic role of docosapentaenoic acid n-3. Version 2. F1000Res. 2013 Nov 25 [revised 2014 Aug 19];2:256. doi: 10.12688/f1000research.2-256.v2. eCollection 2013. Review. PMID 25232466 PMC 4162505
  2. ^ “DPA Nutrient List.” National Nutrient Database for Standard Reference Release 27.

See also[edit]

Original courtesy of Wikipedia: http://en.wikipedia.org/wiki/Docosapentaenoic_acid — Please support Wikipedia.
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80 news items

MedPage Today
Wed, 25 Nov 2015 13:56:15 -0800

... further reported that the synthesis of RvTs was a two-step neutrophil-endothelial interaction process, in which docosapentaenoic acid undergoes metabolism by COX-2 present in the endothelium, and the resulting compound 13-hydroxydocosapentaenoic ...
GlobeNewswire (press release)
Mon, 15 Jun 2015 04:05:53 -0700

"These data demonstrate that MAT9001, a unique omega-3 fatty acid composition with docosapentaenoic acid (DPA), has the potential to expand and to greatly improve therapeutic options for patients with high triglyceride levels and high cholesterol ...

U.S. News & World Report

U.S. News & World Report
Fri, 03 Apr 2015 09:23:44 -0700

ADVERTISING. For the study, researchers from Canada's University of Alberta studied 600 women during and after pregnancy to monitor their intake of omega 3-LCPUFAs. These include DHA, EPA (eicosapentaenoic acid) and DPA (docosapentaenoic acid).

Nutritional Outlook

Nutritional Outlook
Thu, 24 Sep 2015 14:00:00 -0700

The collaboration of researchers ultimately concluded that it is unclear if the modest associations of the fatty acids EPA and docosapentaenoic acid (DPA)—another omega-3 fatty acid—with cancer seen in some studies are causal factors. Overall, the ...
Marketwired (press release)
Thu, 15 Oct 2015 05:56:15 -0700

TP-452, a novel derivative of docosapentaenoic acid (DPA), has potential as adjunct therapy to statins for oral treatment of elevated LDL cholesterol (LDL-C). Nearly 79 million adults in the United States have high LDL-C, and approximately 27 million ...


Tue, 12 May 2015 06:54:20 -0700

... 50 percent of the fat was from fish oil (from menhaden fish); and a control group consisted of healthy, nondiabetic mice. Menhaden fish are an excellent source of not only EPA and DHA, but another fatty acid, docosapentaenoic acid (DPA ...
Wed, 25 Mar 2015 12:18:45 -0700

Omega-3 s include eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA) and docosahexaenoic acid (DHA) — all of which boost fetal development, particularly the brain. The American Dietetic Association and Dietitians of Canada recommend that all ...
Wed, 30 Sep 2015 21:18:45 -0700

Women with evidence of high intake ratios of the marine omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) relative to the omega-6 arachidonic acid have been found to have a reduced risk of breast cancer compared with ...

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