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Docosapentaenoic acid designates any straight chain 22:5 fatty acid.

Isomers[edit]

See essential fatty acid#nomenclature for nomenclature.

all-cis-4,7,10,13,16-docosapentaenoic acid (osbond acid)[edit]

The chemical structure of osbond acid showing physiological numbering (red) and chemical numbering (blue) conventions.


all-cis-4,7,10,13,16-docosapentaenoic acid is an ω-6 fatty acid with the trivial name osbond acid. It is formed by an elongation and desaturation of arachidonic acid 20:4 ω-6.

all-cis-7,10,13,16,19-docosapentaenoic acid (clupanodonic acid)[edit]

The chemical structure of clupanodonic acid showing physiological numbering (red) and chemical numbering (blue) conventions.


all-cis-7,10,13,16,19-docosapentaenoic acid is an ω-3 fatty acid with the trivial name clupanodonic acid, commonly called DPA. It is an intermediary between eicosapentaenoic acid (EPA, 20:5 ω-3) and docosahexaenoic acid (DHA, 22:6 ω-3).

Nutrition[edit]

Docosapentaenoic acid (DPA) is an omega-3 fatty acid that is structurally similar to eicosapentaenoic acid (EPA) with two more carbon chain units.[1]

Dietary sources

These are the top five sources for DPA according to the USDA Agricultural Research Service:[2]

  1. Fish oil, menhaden .668 22:5 n-3 (DPA) (g) Per Measure
  2. Fish oil, salmon .407 22:5 n-3 (DPA) (g) Per Measure
  3. Salmon, red (sockeye), filets with skin, smoked (Alaska Native) 0.335 22:5 n-3 (DPA) (g) Per Measure
  4. Fish, salmon, Atlantic, farmed, raw .334 22:5 n-3 (DPA) (g) Per Measure
  5. Beef, variety meats and by-products, brain, cooked, simmered 22:5 n-3 (DPA) (g) Per Measure

Seal meat and human breast milk are rich in DPA.[1]

Functions[edit]

Clupanodonic acid, an omega-3 fatty acid, along with its metabolite DHA and other long chain omega-3 fatty acids, is under study to determine properties of omega-3 fats in humans, such as in inflammation mechanisms.[3]

References[edit]

See also[edit]


Original courtesy of Wikipedia: http://en.wikipedia.org/wiki/Docosapentaenoic_acid — Please support Wikipedia.
This page uses Creative Commons Licensed content from Wikipedia. A portion of the proceeds from advertising on Digplanet goes to supporting Wikipedia.
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What does docosapentaenoic acid mean?

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Video shows what docosapentaenoic acid means. A polyunsaturated fatty acid having 22 carbon atoms and 5 double bonds. Docosapentaenoic acid Meaning.

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Video shows what DPA means. diphenylanthracene. docosapentaenoic acid. The data protection act. DPA Meaning. How to pronounce, definition audio ...

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121 news items

Nature.com

Nature.com
Tue, 16 Feb 2016 07:33:45 -0800

As for PUFAs, women with psychological distress had lower levels of EPA (20:5 n-3), docosapentaenoic acid (22:5 n-3), and total n-3 PUFAs than controls. DHA did not differ significantly between the two groups. Mean±s.d. data are included in ...

EcoWatch

EcoWatch
Wed, 25 Nov 2015 09:51:41 -0800

Docosapentaenoic acid (DPA). Tetracosapentaenoic acid. Tetracosahexaenoic acid. These fatty acids are found in some foods, but are not considered essential. However, some of of them do have biological effects. Bottom Line: At least 8 other omega-3 ...
 
MedPage Today
Wed, 25 Nov 2015 14:01:13 -0800

... further reported that the synthesis of RvTs was a two-step neutrophil-endothelial interaction process, in which docosapentaenoic acid undergoes metabolism by COX-2 present in the endothelium, and the resulting compound 13-hydroxydocosapentaenoic ...

Natural Products INSIDER

Natural Products INSIDER
Tue, 23 Aug 2011 07:32:31 -0700

The health benefits of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) fatty acids are among the most documented in nutrition research. However, a third key fatty acid, docosapentaenoic acid (DPA)—an intermediary between EPA and DHA, ...
 
Medscape
Wed, 30 Sep 2015 21:18:45 -0700

Women with evidence of high intake ratios of the marine omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) relative to the omega-6 arachidonic acid have been found to have a reduced risk of breast cancer compared with ...
 
Marketwired (press release)
Thu, 15 Oct 2015 05:56:15 -0700

TP-452, a novel derivative of docosapentaenoic acid (DPA), has potential as adjunct therapy to statins for oral treatment of elevated LDL cholesterol (LDL-C). Nearly 79 million adults in the United States have high LDL-C, and approximately 27 million ...

Seeking Alpha

Seeking Alpha
Mon, 01 Jun 2015 11:31:20 -0700

The differentiating aspect of MAT9001 from other omega-3 prescription products is the inclusion of docosapentaenoic acid (DPA) in the optimized mixture. Preclinical studies suggest that DPA has the potential to confer a unique therapeutic profile ...
 
GlobeNewswire (press release)
Mon, 15 Jun 2015 04:05:53 -0700

"These data demonstrate that MAT9001, a unique omega-3 fatty acid composition with docosapentaenoic acid (DPA), has the potential to expand and to greatly improve therapeutic options for patients with high triglyceride levels and high cholesterol ...
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