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Docosapentaenoic acid designates any straight chain 22:5 fatty acid.


See essential fatty acid#nomenclature for nomenclature.

all-cis-4,7,10,13,16-docosapentaenoic acid (osbond acid)[edit]

The chemical structure of osbond acid showing physiological numbering (red) and chemical numbering (blue) conventions.

all-cis-4,7,10,13,16-docosapentaenoic acid is an ω-6 fatty acid with the trivial name osbond acid. It is formed by an elongation and desaturation of arachidonic acid 20:4 ω-6.

all-cis-7,10,13,16,19-docosapentaenoic acid (clupanodonic acid)[edit]

The chemical structure of clupanodonic acid showing physiological numbering (red) and chemical numbering (blue) conventions.

all-cis-7,10,13,16,19-docosapentaenoic acid is an ω-3 fatty acid with the trivial name clupanodonic acid, commonly called DPA. It is an intermediary between eicosapentaenoic acid (EPA, 20:5 ω-3) and docosahexaenoic acid (DHA, 22:6 ω-3).


Docosapentaenoic acid (DPA) is an omega-3 fatty acid that is structurally similar to eicosapentaenoic acid (EPA) with two more carbon chain units.[1]

Dietary sources

These are the top five sources for DPA according to the USDA Agricultural Research Service:[2]

  1. Fish oil, menhaden .668 22:5 n-3 (DPA) (g) Per Measure
  2. Fish oil, salmon .407 22:5 n-3 (DPA) (g) Per Measure
  3. Salmon, red (sockeye), filets with skin, smoked (Alaska Native) 0.335 22:5 n-3 (DPA) (g) Per Measure
  4. Fish, salmon, Atlantic, farmed, raw .334 22:5 n-3 (DPA) (g) Per Measure
  5. Beef, variety meats and by-products, brain, cooked, simmered 22:5 n-3 (DPA) (g) Per Measure

Seal meat and human breast milk are rich in DPA.[1]


Clupanodonic acid, an omega-3 fatty acid, along with its metabolite DHA and other long chain omega-3 fatty acids, is under study to determine properties of omega-3 fats in humans, such as in inflammation mechanisms.[3]


See also[edit]

Original courtesy of Wikipedia: http://en.wikipedia.org/wiki/Docosapentaenoic_acid — Please support Wikipedia.
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134 news items

Chiropractic Economics (press release) (blog)

Chiropractic Economics (press release) (blog)
Fri, 29 Jan 2016 13:22:30 -0800

... dubbed a “pro-EPA” omega-3 fatty acid as it bypasses the Δ6D rate-limiting step in humans that causes plant-derived ALA sources to convert poorly to the more elongated omega-3s of EPA, docosapentaenoic acid (DPA), and docosahexaenoic acid (DHA).
Digital Journal
Wed, 27 Jan 2016 05:52:30 -0800

TP-452 is a unique mineral amino acid-based derivative of n-3 docosapentaenoic acid (DPA) which delivers DPA in a highly bioavailable form following oral administration. Preclinical and clinical observations suggest that DPA has significant effects on ...


Wed, 25 Nov 2015 09:51:41 -0800

Docosapentaenoic acid (DPA). Tetracosapentaenoic acid. Tetracosahexaenoic acid. These fatty acids are found in some foods, but are not considered essential. However, some of of them do have biological effects. Bottom Line: At least 8 other omega-3 ...


Mon, 11 Jan 2016 06:44:01 -0800

Ahiflower consumption was also associated overall docosapentaenoic acid (DPA) accrual versus flaxseed oil and showed significant anti-inflammatory DGLA accrual, whereas overall DGLA actually declined among the subjects consuming flaxseed oil.
MedPage Today
Wed, 25 Nov 2015 13:56:15 -0800

... further reported that the synthesis of RvTs was a two-step neutrophil-endothelial interaction process, in which docosapentaenoic acid undergoes metabolism by COX-2 present in the endothelium, and the resulting compound 13-hydroxydocosapentaenoic ...
Wed, 30 Sep 2015 21:19:16 -0700

Women with evidence of high intake ratios of the marine omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) relative to the omega-6 arachidonic acid have been found to have a reduced risk of breast cancer compared with ...

Nutritional Outlook

Nutritional Outlook
Thu, 24 Sep 2015 14:05:24 -0700

The collaboration of researchers ultimately concluded that it is unclear if the modest associations of the fatty acids EPA and docosapentaenoic acid (DPA)—another omega-3 fatty acid—with cancer seen in some studies are causal factors. Overall, the ...

Seeking Alpha

Seeking Alpha
Mon, 01 Jun 2015 11:31:20 -0700

The differentiating aspect of MAT9001 from other omega-3 prescription products is the inclusion of docosapentaenoic acid (DPA) in the optimized mixture. Preclinical studies suggest that DPA has the potential to confer a unique therapeutic profile ...

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