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Docosapentaenoic acid designates any straight chain 22:5 fatty acid.

Isomers[edit]

See essential fatty acid#nomenclature for nomenclature.

all-cis-4,7,10,13,16-docosapentaenoic acid (osbond acid)[edit]

The chemical structure of osbond acid showing physiological numbering (red) and chemical numbering (blue) conventions.


all-cis-4,7,10,13,16-docosapentaenoic acid is an ω-6 fatty acid with the trivial name osbond acid. It is formed by an elongation and desaturation of arachidonic acid 20:4 ω-6.

all-cis-7,10,13,16,19-docosapentaenoic acid (clupanodonic acid)[edit]

The chemical structure of clupanodonic acid showing physiological numbering (red) and chemical numbering (blue) conventions.


all-cis-7,10,13,16,19-docosapentaenoic acid is an ω-3 fatty acid with the trivial name clupanodonic acid, commonly called DPA. It is an intermediary between eicosapentaenoic acid (EPA, 20:5 ω-3) and docosahexaenoic acid (DHA, 22:6 ω-3).

Nutrition[edit]

Docosapentaenoic acid (DPA) is an omega-3 fatty acid that is structurally similar to eicosapentaenoic acid (EPA) with two more carbon chain units.[1]

Dietary sources

These are the top five sources for DPA according to the USDA Agricultural Research Service: [2]

  1. Fish oil, menhaden .668 22:5 n-3 (DPA) (g) Per Measure
  2. Fish oil, salmon .407 22:5 n-3 (DPA) (g) Per Measure
  3. Salmon, red (sockeye), filets with skin, smoked (Alaska Native) 0.335 22:5 n-3 (DPA) (g) Per Measure
  4. Fish, salmon, Atlantic, farmed, raw .334 22:5 n-3 (DPA) (g) Per Measure
  5. Beef, variety meats and by-products, brain, cooked, simmered 22:5 n-3 (DPA) (g) Per Measure

Seal meat and human breast milk are rich in DPA.[1]

References[edit]

  1. ^ a b Yazdi PG. A review of the biologic and pharmacologic role of docosapentaenoic acid n-3. Version 2. F1000Res. 2013 Nov 25 [revised 2014 Aug 19];2:256. doi: 10.12688/f1000research.2-256.v2. eCollection 2013. Review. PMID 25232466 PMC 4162505
  2. ^ “DPA Nutrient List.” National Nutrient Database for Standard Reference Release 27.

See also[edit]


Original courtesy of Wikipedia: http://en.wikipedia.org/wiki/Docosapentaenoic_acid — Please support Wikipedia.
This page uses Creative Commons Licensed content from Wikipedia. A portion of the proceeds from advertising on Digplanet goes to supporting Wikipedia.
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76 news items

 
SYS-CON Media (press release)
Tue, 04 Aug 2015 07:37:30 -0700

TP-452, a novel derivative of docosapentaenoic acid (DPA), has potential as adjunct therapy to statins for oral treatment of elevated LDL cholesterol (LDL-C). Nearly 79 million adults in the United States have high LDL-C, and approximately 27 million ...
 
GlobeNewswire (press release)
Mon, 15 Jun 2015 04:05:53 -0700

"These data demonstrate that MAT9001, a unique omega-3 fatty acid composition with docosapentaenoic acid (DPA), has the potential to expand and to greatly improve therapeutic options for patients with high triglyceride levels and high cholesterol ...
 
Newsmax
Wed, 25 Mar 2015 12:24:04 -0700

Omega-3 s include eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA) and docosahexaenoic acid (DHA) — all of which boost fetal development, particularly the brain. The American Dietetic Association and Dietitians of Canada recommend that all ...

U.S. News & World Report

U.S. News & World Report
Fri, 03 Apr 2015 09:23:44 -0700

These include DHA, EPA (eicosapentaenoic acid) and DPA (docosapentaenoic acid). DHA is believed to be the biggest player in neurological health and is the primary structural fat found in the brain. The American Dietetic Association recommends that ...

wsnewspublishers

MarketWatch
Wed, 03 Jun 2015 12:41:15 -0700

As for the omega 3 fatty acid molecule itself that differentiates it from the other dyslepidemia drugs, docosapentaenoic acid (DPA), it is a natural molecule found in oily fish just like other omega 3 fatty acids, except it is found in very small ...
 
eMaxHealth
Tue, 12 May 2015 06:54:20 -0700

Menhaden fish are an excellent source of not only EPA and DHA, but another fatty acid, docosapentaenoic acid (DPA). Here's what the researchers discovered: T. he untreated mice had signs of neuropathy—diminished transmission of signals along the ...
 
Seeking Alpha
Mon, 01 Jun 2015 11:31:20 -0700

The differentiating aspect of MAT9001 from other omega-3 prescription products is the inclusion of docosapentaenoic acid (DPA) in the optimized mixture. Preclinical studies suggest that DPA has the potential to confer a unique therapeutic profile ...

Medical Xpress

Medical Xpress
Thu, 02 Jul 2015 04:22:44 -0700

Scientific Opinion on the Tolerable Upper Intake Level of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and docosapentaenoic acid (DPA). EFSA Journal 10(7):2815. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) (2014).
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