Disodium [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolan-2-yl]methyl phosphate
Disodium inosine 5'-monophosphate
Inosine 5'-(disodium phosphate)
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Disodium inosinate (E631) is the disodium salt of inosinic acid with the chemical formula C10H11N4Na2O8P. It is used as a food additive and often found in instant noodles, potato chips, and a variety of other snacks.
Use as a food additive
Disodium inosinate is used as a flavor enhancer, in synergy with monosodium glutamate (MSG) to provide the umami taste. It is often added to foods in conjunction with disodium guanylate; the combination is known as disodium 5'-ribonucleotides.
As a relatively expensive product, disodium inosinate is usually not used independently of glutamic acid; if disodium inosinate is present in a list of ingredients, but MSG does not appear to be, it is possible that glutamic acid is provided as part of another ingredient or is naturally occurring in another ingredient like tomatoes, Parmesan cheese or yeast extract.
Disodium inosinate, also known as disodium 5’-inosinate, comes from nucleotide, inosine monophosphate (IMP).In the flavor industry, disodium inosinate and disodium guanylate together known as disodium ribotides (“I + G.”).A small amount of I + G may be added to a food to replace some monosodium glutamate (MSG).Leading manufacturers of disodium guanylate and disodium inosinate produce I + G by microbial fermentation. Their growth media usually consisting mainly of tapioca starch. Few companies also produce I + G from yeast.
Toxicology and safety
In the United States, consumption of added 5'-ribonucleotides averages 4 mg per day, compared to 2 g per day of naturally occurring purines. A review of literature by an FDA committee found no evidence of carcinogenicity, teratogenicity, or adverse effects on reproduction.
In 2004, disodium inosinate was removed from the food additive list by Codex Alimentarius Commission (but it is still mentioned on the last (2009) codex alimentarius list).
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Fri, 12 Sep 2014 10:01:32 -0700
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Tue, 16 Sep 2014 09:07:30 -0700
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Tue, 09 Sep 2014 00:08:54 -0700
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