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De Gradibus was an Arabic book published by the Arab physician Al-Kindi (c. 801–873 CE). De gradibus is the Latinized name of the book. An alternative name for the book was Quia Primos.^[1]

In De Gradibus, Al-Kindi attempts to apply mathematics to pharmacology by quantifying the strength of drugs. According to Prioreschi, this was the first attempt at serious quantification in medicine.^[2] He also developed a system, based on the phases of the Moon, that would allow a doctor to determine in advance the most critical days of a patient's illness.^[3] During the Arabic-Latin translation movement of the 12th century, De Gradibus was translated into Latin by Gerard of Cremona.^[1] Al-Kindi's mathematical reasoning was complex and hard to follow; Roger Bacon commented that his method of computing the strength of a drug was extremely difficult to use.^[2]

References [edit]

^ ^a ^b p. 19, "Al-Kindi, A Precursor Of The Scientific Revolution", Plinio Prioreschi, Journal of the International Society for the History of Islamic Medicine 1, #2 (October 2002), pp. 17–19.
^ ^a ^b p. 18, Prioreschi 2002.
^ (incomplete citation) Klein-Franke, p. 172

Medicine in the medieval Islamic world

Physicians

7th century	Al-Harith ibn Kalada and his son Abu Hafsa Yazid Bukhtishu Masarjawaih Ibn Abi Ramtha al-Tamimi Rufaida Al-Aslamia Ibn Uthal

8th century	Bukhtishu family Ja'far al-Sadiq

9th century	Albubather Bukhtishu family Jabril ibn Bukhtishu Jābir ibn Hayyān Hunayn ibn Ishaq and his son Yahya ibn Sarafyun Al-Kindi Masawaiyh Sabur ibn Sahl Ali ibn Sahl Rabban al-Tabari Al-Ruhawi Yuhanna ibn Bukhtishu Salmawaih ibn Bunan

10th century	Qusta ibn Luqa Abu ul-Ala Shirazi Abul Hasan al-Tabari Al-Natili Qumri Abu Zayd al-Balkhi Isaac Israeli ben Solomon Ali ibn Abbas al-Majusi Abu Sahl 'Isa ibn Yahya al-Masihi Muvaffak Muhammad ibn Zakariya al-Razi Ibn Juljul Al-Zahrawi Ibn al-Jazzar Al-Kaŝkarī Ibn Abi al-Ashʿath Ibn al-Batriq Ibrahim ibn Baks

11th century	Abu Ubaid Juzjani Alhazen Ali ibn Ridwan Avicenna Ephraim ibn al-Za'faran Ibn al-Wafid Abdollah ibn Bukhtishu Ibn Butlan Ibn al-Kattani Ibn Jazla Masawaih al-Mardini Yusuf al-Ilaqi Ibn Al-Thahabi Ibn Abi Sadiq Ali ibn Isa al-Kahhal

12th century	Abu al-Bayan ibn al-Mudawwar Ahmad ibn Farrokh Ibn Hubal Zayn al-Din Gorgani Maimonides Serapion the Younger Ibn Zuhr Ya'qub ibn Ishaq al-Israili Abu Jafar ibn Harun of Trujillo Averroes Ibn Tufail Al-Ghafiqi Ibn Abi al-Hakam Abu'l-Barakāt al-Baghdādī Samauʼal Al-Maghribī Ibn al-Tilmīdh Ibn Jumay‘

13th century	Sa'ad al-Dawla Al-Shahrazuri Rashidun al-Suri Amin al-Din Rashid al-Din Vatvat Avraham son of Rambam Da'ud Abu al-Fadl Al-Dakhwar Ibn Abi Usaibia Joseph ben Judah of Ceuta Abd al-Latif al-Baghdadi (medieval writer) Ibn al-Nafis Zakariya al-Qazwini Najib ad-Din-e-Samarqandi Qotb al-Din Shirazi Ibn al-Quff

14th century	Muhammad ibn Mahmud Amuli Al-Nagawri Aqsara'i Zayn-e-Attar Mansur ibn Ilyas Jaghmini Mas‘ud ibn Muhammad Sijzi Najm al-Din Mahmud ibn Ilyas al-Shirazi Nakhshabi Sadid al-Din al-Kazaruni Yusuf ibn Ismail al-Kutubi Ibn al-Khatib Rashid-al-Din Hamadani

15th century	Abu Sa'id al-Afif Muhammad Ali Astarabadi Husayni Isfahani Burhan-ud-din Kermani Şerafeddin Sabuncuoğlu Muhammad ibn Yusuf al-Harawi Nurbakhshi Shaykh Muhammad ibn Thaleb

16th century	Hakim-e-Gilani Abul Qasim ibn Mohammed al-Ghassani Taqi al-Din Muhammad ibn Ma'ruf Dawud al-Antaki

Concepts

Works

Centers

Influences

Ancient Greek medicine

Influenced

Mathematics in medieval Islam

Mathematicians

9th century	'Abd al-Hamīd ibn Turk Sind ibn Ali Al-Abbās ibn Said al-Jawharī Al-Ḥajjāj ibn Yūsuf ibn Maṭar Al-Kindi Al-Mahani Banū Mūsā Hunayn ibn Ishaq Muḥammad ibn Mūsā al-Khwārizmī Thābit ibn Qurra Na'im ibn Musa Sahl ibn Bishr Habash al-Hasib al-Marwazi

10th century	Abd al-Rahman al-Sufi Abū al-Wafā' al-Būzjānī Abū Ja'far al-Khāzin Abū Kāmil Shujāʿ ibn Aslam Abu'l-Hasan al-Uqlidisi Abu-Mahmud Khojandi Ahmad ibn Yusuf Al-Nayrizi Al-Saghani Brethren of Purity Ibn Sahl Ibn Yunus Ibrahim ibn Sinan Muhammad ibn Jābir al-Harrānī al-Battānī Sinan ibn Thabit Al-Isfahani Abu-Mahmud Khojandi Nazif ibn Yumn Abū Sahl al-Qūhī

11th century	Abū Ishāq Ibrāhīm al-Zarqālī Abu Nasr Mansur Abū Rayḥān al-Bīrūnī Alhazen Ibn Muʿādh al-Jayyānī Al-Karaji Al-Sijzi Alī ibn Ahmad al-Nasawī Avicenna Ibn Tahir al-Baghdadi Kushyar ibn Labban Yusuf al-Mu'taman ibn Hud

12th century	Al-Khazini Ibn Yahyā al-Maghribī al-Samaw'al Omar Khayyám Jabir ibn Aflah Abu Bakr al-Hassar

13th century	Muhyi al-Dīn al-Maghribī Nasīr al-Dīn al-Tūsī Shams al-Dīn al-Samarqandī Sharaf al-Dīn al-Tūsī Ibn al‐Ha'im al‐Ishbili Ibn Abi al-Shukr

14th century	Yaʿīsh ibn Ibrāhīm al-Umawī Ibn al-Banna' al-Marrakushi Ibn al-Shatir Kamāl al-Dīn Fārisī Al-Khalili Qotb al-Din Shirazi Ahmad al-Qalqashandi

15th century	Abū al-Ḥasan ibn ʿAlī al-Qalaṣādī Ali Qushji Jamshīd al-Kāshī Qāḍī Zāda al-Rūmī Ulugh Beg Ibn al-Majdi

16th century	Al-Birjandi Muhammad Baqir Yazdi Taqi al-Din Ibn Hamza al-Maghribi Ibn Ghazi al-Miknasi

Treatises

Almanac
Book of Fixed Stars
Book of Optics
De Gradibus
Encyclopedia of the Brethren of Purity
Tables of Toledo
Tabula Rogeriana
The Compendious Book on Calculation by Completion and Balancing
The Book of Healing
Zij
Zij-i Ilkhani
Zij-i-Sultani

Concepts

Alhazen's problem

Centers

Influences

Influenced

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De Gradibus

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