digplanet beta 1: Athena
Share digplanet:

Agriculture

Applied sciences

Arts

Belief

Business

Chronology

Culture

Education

Environment

Geography

Health

History

Humanities

Language

Law

Life

Mathematics

Nature

People

Politics

Science

Society

Technology

Overview of human "circadian biological clock" with some physiological parameters.

Chronobiology is a field of biology that examines periodic (cyclic) phenomena in living organisms and their adaptation to solar- and lunar-related rhythms.[1] These cycles are known as biological rhythms. Chronobiology comes from the ancient Greek χρόνος (chrónos, meaning "time"), and biology, which pertains to the study, or science, of life. The related terms chronomics and chronome have been used in some cases to describe either the molecular mechanisms involved in chronobiological phenomena or the more quantitative aspects of chronobiology, particularly where comparison of cycles between organisms is required.

Chronobiological studies include but are not limited to comparative anatomy, physiology, genetics, molecular biology and behavior of organisms within biological rhythms mechanics.[1] Other aspects include development, reproduction, ecology and evolution.

Description[edit]

The variations of the timing and duration of biological activity in living organisms occur for many essential biological processes. These occur (a) in animals (eating, sleeping, mating, hibernating, migration, cellular regeneration, etc.), (b) in plants (leaf movements, photosynthetic reactions, etc.), and in microbial organisms such as fungi and protozoa. They have even been found in bacteria, especially among the cyanobacteria (aka blue-green algae, see bacterial circadian rhythms). The most important rhythm in chronobiology is the circadian rhythm, a roughly 24-hour cycle shown by physiological processes in all these organisms. The term circadian comes from the Latin circa, meaning "around" and dies, "day", meaning "approximately a day." It is regulated by circadian clocks.

The circadian rhythm can further be broken down into routine cycles during the 24-hour day:[2]

  • Diurnal, which describes organisms active during daytime
  • Nocturnal, which describes organisms active in the night
  • Crepuscular, which describes animals primarily active during the dawn and dusk hours (ex: white-tailed deer, some bats)

While circadian rhythms are defined as endogenously regulated, other biological cycles may be regulated by exogenous signals. In some cases, multi-trophic systems may exhibit rhythms driven by the circadian clock of one of the members (which may also be influenced or reset by external factors). The endogenous plant cycles may regulate the activity of the bacterium by controlling availability of plant-produced photosynthate.

Many other important cycles are also studied, including:

Within each cycle, the time period during which the process is more active is called the acrophase.[3] When the process is less active, the cycle is in its bathyphase or trough phase. The particular moment of highest activity is the peak or maximum; the lowest point is the nadir. How high (or low) the process gets is measured by the amplitude.

History[edit]

A circadian cycle was first observed in the 18th century in the movement of plant leaves by the French scientist Jean-Jacques d'Ortous de Mairan (for a description of circadian rhythms in plants by de Mairan, Linnaeus, and Darwin see this page). In 1751 Swedish botanist and naturalist Carolus Linnaeus (Carl von Linné) designed a flower clock using certain species of flowering plants. By arranging the selected species in a circular pattern, he designed a clock that indicated the time of day by the flowers that were open at each given hour. For example, among members of the daisy family, he used the hawk's beard plant which opened its flowers at 6:30 am and the hawkbit which did not open its flowers until 7 am.[4]

The 1960 symposium at Cold Spring Harbor Laboratory laid the groundwork for the field of chronobiology.[5]

It was also in 1960 that Patricia DeCoursey invented the phase response curve, one of the major tools used in the field since.

Franz Halberg of the University of Minnesota, who coined the word circadian, is widely considered the "father of American chronobiology." However, it was Colin Pittendrigh and not Halberg who was elected to lead the Society for Research in Biological Rhythms in the 1970s. Halberg wanted more emphasis on the human and medical issues while Pittendrigh had his background more in evolution and ecology. With Pittendrigh as leader, the Society members did basic research on all types of organisms, plants as well as animals. More recently it has been difficult to get funding for such research on any other organisms than mice, rats, humans[6][7] and fruit flies.

Recent developments[edit]

More recently, light therapy and melatonin administration have been explored by Dr. Alfred J. Lewy (OHSU), Dr. Josephine Arendt (University of Surrey, UK) and other researchers as a means to reset animal and human circadian rhythms. Additionally, the presence of low-level light at night accelerates circadian re-entrainment of hamsters of all ages by 50%; this is thought to be related to simulation of moonlight.[8]

Humans can be morning people or evening people; these variations are called chronotypes for which there are various assessment tools and biological markers.

In the second half of 20th century, substantial contributions and formalizations have been made by Europeans such as Jürgen Aschoff and Colin Pittendrigh, who pursued different but complementary views on the phenomenon of entrainment of the circadian system by light (parametric, continuous, tonic, gradual vs. nonparametric, discrete, phasic, instantaneous, respectively; see this historical article, subscription required).

There is also a food-entrainable biological clock, which is not confined to the suprachiasmatic nucleus. The location of this clock has been disputed. Working with mice, however, Fuller et al. concluded that the food-entrainable clock seems to be located in the dorsomedial hypothalamus. During restricted feeding, it takes over control of such functions as activity timing, increasing the chances of the animal successfully locating food resources.[9]

Other fields[edit]

Chronobiology is an interdisciplinary field of investigation. It interacts with medical and other research fields such as sleep medicine, endocrinology, geriatrics, sports medicine, space medicine and photoperiodism.[10][11][12]

The notion of biorhythms, a classic example of pseudoscience, which attempts to describe a set of cyclic variations in human behavior based on physiological and emotional cycles, is not a part of chronobiology.[13]

See also[edit]

References[edit]

  1. ^ a b Patricia J. DeCoursey; Jay C. Dunlap; Jennifer J. Loros (2003). Chronobiology. Sinauer Associates Inc. ISBN 978-0-87893-149-1. 
  2. ^ Nelson RJ. 2005. An Introduction to Behavioral Endocrinology. Sinauer Associates, Inc.: Massachusetts. Pg587.
  3. ^ Refinetti, Roberto (2006). Circadian Physiology. CRC Press/Taylor & Francis Group. ISBN 0-8493-2233-2. Lay summary
  4. ^ http://www.linnean.org/Resources/LinneanSociety/Documents/Library-and-Archives/4-Floral%20Clock.pdf
  5. ^ Leon Kreitzman; Russell G. Foster (2004). Rhythms of life: the biological clocks that control the daily lives of every living thing. New Haven, Conn: Yale University Press. ISBN 0-300-10969-5. 
  6. ^ Zivkovic, Bora (2006-07-03). "ClockTutorial #2a, Forty-Five Years of Pittendrigh's Empirical Generalizations". A Blog Around the Clock. ScienceBlogs. Retrieved 2007-12-23. 
  7. ^ Zivkovic, Bora (2006-05-17). "Clocks in Bacteria V". A Blog Around the Clock. ScienceBlogs. Retrieved 2007-12-23. 
  8. ^ Frank, D. W.; Evans, J. A.; Gorman, M. R. (2010). "Time-Dependent Effects of Dim Light at Night on Re-Entrainment and Masking of Hamster Activity Rhythms". Journal of Biological Rhythms 25 (2): 103–112. doi:10.1177/0748730409360890. PMID 20348461.  edit
  9. ^ Fuller, Patrick M.; Jun Lu; Clifford B. Saper (2008-05-23). "Differential Rescue of Light- and Food-Entrainable Circadian Rhythms" (free abstract). Science 320 (5879): 1074–1077. Bibcode:2008Sci...320.1074F. doi:10.1126/science.1153277. PMID 18497298. Retrieved 2008-05-30. 
  10. ^ Postolache, Teodor T. (2005). Sports Chronobiology, An Issue of Clinics in Sports Medicine. Saunders. ISBN 978-1-4160-2769-0. 
  11. ^ Ernest Lawrence Rossi, David Lloyd (1992). Ultradian Rhythms in Life Processes: Inquiry into Fundamental Principles of Chronobiology and Psychobiology. Springer-Verlag Berlin and Heidelberg GmbH & Co. K. ISBN 978-3-540-19746-1. 
  12. ^ Hayes, D.K. (1990). Chronobiology: Its Role in Clinical Medicine, General Biology, and Agriculture. John Wiley & Sons. ISBN 978-0-471-56802-5. 
  13. ^ "Effects of circadian rhythm phase alteration on physiological and psychological variables: Implications to pilot performance (including a partially annotated bibliography)". NASA-TM-81277. NASA. 1981-03-01. Retrieved 2011-05-25.  "No evidence exists to support the concept of biorhythms; in fact, scientific data refute their existence."

Further reading[edit]

External articles[edit]


Original courtesy of Wikipedia: http://en.wikipedia.org/wiki/Chronobiology — Please support Wikipedia.
This page uses Creative Commons Licensed content from Wikipedia. A portion of the proceeds from advertising on Digplanet goes to supporting Wikipedia.
1211 videos foundNext > 

Natural Solutions with Chronobiology With John Andrews, Master Herbalist & Iridologist

Natural Solutions with Chronobiology With John Andrews, Master Herbalist & Iridologist It isn't just about what supplements we take, but about when we take t...

New ideas in chronobiology | Tomorrow Today - Interview

Dr. Dieter Kunz of the Charité Hospital in Berlin talks about some of the latest ideas in chronobiology, and to what extent they do - and don't - affect our ...

Open Mind / Process Time, what makes us tick?

WATCH FULL SCREEN! This is a docu-video about the process of Open Mind; Time, what makes us tick? In august 2010 Pavlov E-lab presented another Open Mind edi...

Chronobiology.m4v

Dr. Susan Steigerwalt discusses the latest advances from the world of chronobiology.

Stu Brody History of Chronobiology at UCSD Presentation

Stu Brody History of Chronobiology at UCSD Presentation.

Research Spotlight: Chronobiology Lab

Research Spotlight: Chronobiology Lab For more information please visit psyc.ucalgary.ca.

Time Matters: Chronobiology and Cancer Treatment

Topic: Time Matters: Chronobiology and Cancer Treatment -- The Science of Getting Prevention, Treatment, and Recovery in Synch. Guest: Donald L. McEachron, P...

How to Pronounce Chrono Biology

Can we reach 1 Like? Watch video to the end :) World English Dictionary chronobiology (ˌkrɒnəbaɪˈɒlədʒɪ, ˌkrəʊnə-) biological clock See also circadian the branch of biology...

UCSD Conversations: Cross-Cultural Medicine Chronobiology

Join Pat Ledden for a discussion on International Health and Cross-Cultural Medicine with Dr. Harold J. Simon, Chief of International Health and Cross Cultural Medicine. Then meet Sia Nemat-Nasser,...

Seasonal Facial Autumn-Winter 2012: Blackberry-Apple / Limited Edition Sothys | Chronobiology

Seasonal Facial Autumn-Winter 2012: Blackberry-Apple Limited Edition Sothys | Chronobiology Sothys, Exclusively in institutes & spas. http://www.sothys.com F...

1211 videos foundNext > 

37 news items

WallStreet OTC

WallStreet OTC
Wed, 23 Jul 2014 06:18:45 -0700

“When people are sleepy, they make poor food choices and are more likely to eat more than they need,” said Kenneth Wright, director of sleep and chronobiology laboratory at the University of Colorado in Boulder. Wright further said, “When those folks ...

University Herald

University Herald
Mon, 21 Jul 2014 14:22:30 -0700

"When people are sleepy, they make poor food choices and are more likely to eat more than they need," Kenneth Wright, director of sleep and chronobiology laboratory at the University of Colorado in Boulder, told USA Today. Wright said when people got ...
 
Yahoo News
Mon, 21 Jul 2014 05:31:57 -0700

Siffre was a French scientist and a pioneer in chronobiology, which is the study of biological rhythms. The most well-known of these biological rhythms is the circadian rhythm, which controls the human sleep-wake cycle, and Siffre was on a mission to ...
 
Dynamic Chiropractic
Tue, 08 Jul 2014 09:33:59 -0700

Blask D. "Melatonin: An Integrative Chronobiotic Anticancer Therapy Whose Time Has Come." National Cancer Institute Office of Cancer Complementary and Alternative Medicine; Invited Speaker Series: Melatonin, Chronobiology and Cancer.
 
Wall St. Cheat Sheet
Sat, 12 Jul 2014 15:18:42 -0700

Although different findings have been reported on this matter over the past decade on sleep research, The New York Times describes a particularly enlightening 2003 study by Dr. David Dinges – the head of the Sleep and Chronobiology Laboratory at the ...

Wall St. Cheat Sheet

Wall St. Cheat Sheet
Sat, 05 Jul 2014 10:36:28 -0700

“While the timing of work may not be flexible, giving up some TV viewing in the evening should be possible to promote adequate sleep,” said Dr. Mathias Basner of the Division of Sleep and Chronobiology at University of Pennsylvania to The Telegraph.

Medical Daily

Medical Daily
Thu, 10 Jul 2014 08:45:00 -0700

Circadian rhythms are also known as the study of chronobiology. Each individual, regardless of age, has a specific chronotype, or internal timer, that is thought to be designed by our DNA and not by environmental factors. It is what is believed to ...

Medical Daily

Medical Daily
Sun, 29 Jun 2014 17:56:15 -0700

They found night owls drove poorly in the morning. Sleep Medicine has evolved over the past 25 years based on the convergence of major developments in the science of sleep and circadian rhythms (chronobiology). Each individual, regardless of their age, ...
Loading

Oops, we seem to be having trouble contacting Twitter

Talk About Chronobiology

You can talk about Chronobiology with people all over the world in our discussions.

Support Wikipedia

A portion of the proceeds from advertising on Digplanet goes to supporting Wikipedia. Please add your support for Wikipedia!