digplanet beta 1: Athena
Share digplanet:


Applied sciences






















Cetrimonium bromide
Cetyltrimethyl ammonium bromide.svg
CAS number 57-09-0 YesY
PubChem 5974
ChemSpider 5754 YesY
KEGG D03454 YesY
ATC code D08AJ02, R02AA17
Jmol-3D images Image 1
Molecular formula C19H42BrN
Molar mass 364.45 g/mol
Appearance white powder
Melting point 237–243 °C (decomposes)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

Cetrimonium bromide ((C16H33)N(CH3)3Br, cetyltrimethylammonium bromide, hexadecyltrimethylammonium bromide, CTAB) is one of the components of the topical antiseptic cetrimide.[1] The cetrimonium (or hexadecyltrimethylammonium) cation is an effective antiseptic agent against bacteria and fungi.

It is a cationic surfactant. Its uses include providing a buffer solution for the extraction of DNA. It has been widely used in synthesis of gold nanoparticles (e.g., spheres, rods, bipyramids) and mesoporous silica nanoparticles (e.g., MCM-41). It is also widely used in hair conditioning products.

As any surfactant, it forms micelles in aqueous solutions. At 303 K (30 °C) it forms micelles with aggregation number 75-120 (depending on method of determination, usually average ~95) and degree of ionization α (fractional charge) 0.2–0.1 (from low to high concentration).

The standard constant of Br- counterion binding to the micelle at 303 K (30 °C) is K° ≈ 400. This value is calculated from Br- and CTA+ ion selective electrode measurements and conductometry data by using literature data for micelle size (r = ~3 nm), extrapolated to the critical micelle concentration of 1 mM. However, it varies with total surfactant concentration so it is extrapolated to the point at which the concentration of micelles is zero)

The closely related compounds cetrimonium chloride and cetrimonium stearate are also used as topic antiseptics, and may be found in many household products such as shampoos and cosmetics, while cetrimonium bromide, due to its high cost, is only found in select cosmetics.

Use of CTAB in protein electrophoresis[edit]

Because of the broad distribution of negative charges in glycoproteins, these form broad, fuzzy bands in SDS-PAGE (Laemmli-electrophoresis).[2] This can be avoided by using positively charged detergents like CTAB [3][4] instead of the negatively charged SDS. Proteins can be blotted from CTAB-gels in analogy to western blots ("eastern blot"), and CTAB-PAGE can be used as second dimension after IEF. Myelin-associated high hydrophobic protein can be analyzed using CTAB 2-DE.

See also[edit]


  1. ^ Ito., Emma (November 2009). "Editorial". Potential Use of Cetrimonium Bromide as an Apoptosis-Promoting Anticancer Agent for Head and Neck Cancer 76 (5): 969–983. Retrieved November 2009. 
  2. ^ Laemmli, UK (1970). "Cleavage of structural proteins during the assembly of the head of bacteriophage T4". Nature 227 (5259): 680–5. doi:10.1038/227680a0. PMID 5432063. 
  3. ^ Buxbaum, Engelbert (2003). "Cationic electrophoresis and electrotransfer of membrane glycoproteins". Analytical Biochemistry 314 (1): 70–6. doi:10.1016/S0003-2697(02)00639-5. PMID 12633604. 
  4. ^ E. Buxbaum: Cationic electrophoresis and eastern blotting. In: B.T. Kurien & R.H. Scofield (ed): Protein blotting and detection – Methods and protocols, (Meth. Mol. Biol. 536), Dordrecht (Humana) 2009, ISBN 978-1-934115-73-2, pp. 115–28

Further reading[edit]

Original courtesy of Wikipedia: http://en.wikipedia.org/wiki/Cetrimonium_bromide — Please support Wikipedia.
This page uses Creative Commons Licensed content from Wikipedia. A portion of the proceeds from advertising on Digplanet goes to supporting Wikipedia.
52 videos foundNext > 

Cetrimonium Bromide

Learn what ingredients help and harm your hair. This is a review of ingredients that are found in some of the most popular hair and skin care products. Be an...

cetrimonium bromide

Not all ingredients are bad, even the ones we can't easily pronounce. This is a common ingredient found in cosmetic products facial products make-up and yes!...

"Feed Me" DIY Conditioner For Dry Hair ~ The Recipe

Resources & comments: https://www.nenonatural.com/diyconditioners.html INGREDIENTS Heated oil phase (38%) - 4g BTMS-50 (4%) - 2g Cetrimonium bromide (2%) - 2...

"Feed Me" DIY Moisturizer For Dry Hair ~ The Tutorial

Resources & comments: https://www.nenonatural.com/diymoisturizers.html INGREDIENTS Heated oil phase (17%) • 1g BTMS-50 (1%) • 1g Cetrimonium bromide (1%) • 1...

"Love Me" DIY Moisturizer For Weak & Brittle Hair ~ The Tutorial

Resources & comments: https://www.nenonatural.com/diymoisturizers.html INGREDIENTS Heated oil phase (8%) - 1g BTMS-50 (1%) - 1g Incroquat CR (1%) - 1g cetrim...

Loreal Mizellentechnologie Reinigungsfluid vs. Bioderma Sensibio H2O

Inhaltsstoffe: L´oreal Aqua/Water, Hexylene Glycol, Glycerin, Poloxamer, Disodium Coco-amphodiacetate, Disodium edta, Polyaminopropyl, Biguanide. Bioderma Wa...

Use up the Stash Aug 2013

EO Essentials: Purified Water, Behentrimonium Methosulfate (and) Cetearyl Alcohol, Vegetable Glycerin, Organic Jojoba (Simmondsia chinensis) Oil, Glyceryl St...

32***Taliah Waajid Protective Mist Bodifier

FYI: Its 7.99 at Sallys however it can be found different places for cheaper. Sorry forgot to add that. Price: $6-$8 depending on where you get it at. Ingred...

Quest for the Perfect Deep Conditioner Vol 4 Nutress Hair Protein Pack

Purchased this after seeing MahoganyKnots use it. I loved it! Will replace aphogee for me if I'm in need of protein and increasing the clumpage of my curls. ...

Tutorial Pulizia del Viso

ciao ragazze :) questo video mi è stato chiesto da tantissime ragazze! spero vi sia utile e per qualiasi cosa io sono qui :) un bacione grande!! DETERGENTE A...

52 videos foundNext > 

7 news items

Korea JoongAng Daily
Thu, 04 Sep 2014 14:41:35 -0700

The Environmental Working Group, an health research and advocacy organization, said cetrimonium bromide is a skin toxicant and allergen. However, it also said the substance is “safe for use in cosmetics, subject to concentration or use limitations.”


Fri, 05 Sep 2014 07:49:35 -0700

수개월 전 MBC '불만제로UP'에서 시판 중인 영유아 물티슈 23개 제품 중 6개에서 가습기 살균제의 한 성분인 클로로메틸이소치아졸리논(CMIT)과 메칠이소치아졸리논(MIT)이 검출됐다. CMIT와 MIT는 폐 손상을 유발하는 물질로, 이로 인해 많은 피해가 발생하였던 ...


Wed, 17 Sep 2014 20:00:00 -0700

얼마 전 한 언론 매체에서 일부 아기 물티슈 브랜드에서 '세트리모늄 브로마이드(Cetrimonium Bromide)' 성분이 함유된 제품이 시중에 유통되고 있다고 보도해 물티슈 시장에 파장이 일어났다. 이에 산업통상자원부가 물티슈 속 유해성분에 대한 입장을 밝히며 일단 ...


Mon, 01 Sep 2014 23:19:38 -0700

... [티브이데일리 조해진 기자] 물티슈 성분 '세트리모늄브로마이드(Cetrimonium Bromide)'에 대한 공방이 뜨거운 가운데 몽드드가 국가공인시험인증기관으로부터 검증받은 경구독성테스트 시험성적서와 시민단체의 조사 결과를 공개해 눈길을 끌고 있다.


Wed, 03 Sep 2014 01:37:30 -0700

한편, 지난달 30일 한 언론 매체에서는 “대다수의 물티슈 업체에서 신생아와 임산부에게 유해한 화학성분으로 알려진 4급 암모늄 브롬 화합물인 '세트리모늄 브로마이드(Cetrimonium Bromide)'를 지난해 8월부터 사용하고 있다는 사실을 확인했다”고 보도했다.


Thu, 11 Sep 2014 02:56:15 -0700

환경정의, 환경운동연합 등이 참여하고 있는 발암물질없는사회만들기국민행동(http://nocancer.kr, 이하 발암물질국민행동)은 유해성 논란이 휩싸인 물티슈 성분인 '세트리모늄브로마이드'(Cetrimonium Bromide)에 대한 부모들의 이해를 돕기 위해 11일 공식 논평을 ...


Tue, 02 Sep 2014 22:36:03 -0700

발암물질없는사회만들기국민행동(이하 발암물질국민행동)은 최근 영유아용 물티슈에 들어있다고 논란이 된 '세트리모늄브로마이드(Cetrimonium Bromide)' 유해성에 대해 공식 입장을 2일 발표했다. 발암물질국민행동은 환경운동연합, 참교육학부모회, 노동환경 ...

Oops, we seem to be having trouble contacting Twitter

Support Wikipedia

A portion of the proceeds from advertising on Digplanet goes to supporting Wikipedia. Please add your support for Wikipedia!