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5273 news items

Nature.com

Nature.com
Mon, 01 Feb 2016 03:03:45 -0800

To explore key node genes in the TME during oral carcinogenesis, epithelia and fibroblasts from the sequential stages of neoplasia, namely the normal, dysplasia and SCC stages (three rat epithelia/fibroblasts per sample, three samples per group), were ...
 
UroToday
Thu, 11 Feb 2016 14:41:15 -0800

Here we evaluated the chemopreventive effect of a kavalactone-rich Kava fraction B (KFB), free of flavokavains, on carcinogenesis in a transgenic adenocarcinoma of mouse prostate (TRAMP) model and characterized the prostate gene expression signatures ...

Nature.com

Nature.com
Fri, 15 Jan 2016 04:40:32 -0800

CpG methylation is a central mechanism of epigenetic gene regulation affecting cancer-related genes, and occurs early in gastric carcinogenesis. DNA samples from non-metaplastic gastric mucosa with variable levels of gastritis (non-metaplastic mucosa), ...
 
Diagnostic Imaging
Fri, 12 Feb 2016 11:41:15 -0800

The article, by authors from the FDA Center for Devices and Radiological Health in Rockville, MD, and Loyola University in Chicago, IL, sought to examine the origination of the linear no-threshold (LNT) model with respect to genetic effects and ...

KVAL

KVAL
Wed, 10 Feb 2016 12:37:30 -0800

Research has also shown that sulforaphane, which is found at the highest levels in such foods, can modulate breast cancer risk at several stages of carcinogenesis and through different mechanisms. In particular, sulforaphane appears to inhibit histone ...

Nature.com

Nature.com
Fri, 12 Feb 2016 04:41:19 -0800

The melanoma revolution: from UV carcinogenesis to a new era in therapeutics. Science 2014;346:945–949. | Article | PubMed | ISI |; Powles T, Eder JP, Fine GD et al. MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer.

Nature.com

Nature.com
Tue, 09 Feb 2016 22:00:00 -0800

Surprisingly, studies in mouse models dissecting temporal dynamics of epithelial wound healing mimicking carcinogenesis showed that microbial symbionts, for example Lactobacillus reuteri, served to briefly stimulate inflammation for constructive wound ...

dailyRx News

dailyRx News
Thu, 11 Feb 2016 10:22:30 -0800

"The causal factor behind the association appears to play a notable role in lung carcinogenesis, worthy of consideration by researchers, health providers, and the general public," the study authors said. According to the Centers for Disease Control and ...
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