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2753 news items

 
Nature.com
Mon, 17 Aug 2015 03:02:48 -0700

In both humans with long-standing ulcerative colitis and mouse models of colitis-associated carcinogenesis (CAC), tumors develop predominantly in the distal part of the large intestine but the biological basis of this intriguing pathology remains unknown.

KMTV

North Platte Bulletin
Tue, 25 Aug 2015 18:30:00 -0700

Services were held today for Sidney Mirvish, Ph.D., a professor emeritus in the Eppley Institute for Research in Cancer and Allied Diseases at the University of Nebraska Medical Center whose pioneering research into nitrosamines and carcinogenesis led ...

Nature.com

Nature.com
Thu, 27 Aug 2015 05:11:15 -0700

PRKACA and PRKACB encode catalytic subunits of cyclic AMP (cAMP)-dependent protein kinases, which have been implicated in carcinogenesis through activation of the mitogen-activated protein kinase (MAPK) signaling axis. The PRKACA and PRKACB ...
 
Nature.com
Thu, 27 Aug 2015 02:45:00 -0700

It was shown that genetic variants in FAM13A gene may determine susceptibility to COPD and lung cancer. The Rho GTPases activity regulation may indicated the potential role of FAM13A in carcinogenesis. Several such modulators of these type in immune ...
 
PR Newswire (press release)
Thu, 25 Jun 2015 08:00:00 -0700

There are today 230 companies plus partners developing 280 viral carcinogenesis targeting drugs in 1123 developmental projects in cancer. In addition, there are 2 suspended drugs and the accumulated number of ceased drugs over the last years amount to ...
 
Nature.com
Sun, 23 Aug 2015 23:00:00 -0700

... found that in mice colonized with enterotoxigenic Bacteroides fragilis (ETBF) — a human colonic bacterium associated with inflammatory intestinal diseases — TReg cells produce interleukin-17, which promotes the earliest stages of colon ...
 
Nature.com
Mon, 24 Aug 2015 06:18:45 -0700

Because of the central role of mTOR in cancer biology, its inhibitors are targets for the development of anticancer drugs. Many of the genetic alterations responsible for colorectal carcinogenesis act through the mTOR pathway, suggesting that mTOR ...

CBS News

Medscape
Mon, 24 Aug 2015 14:05:36 -0700

It takes that long for the change to flow up the river; that is similar for carcinogenesis," he added. Although the findings confirm the protective effects of aspirin and nonaspirin NSAIDs against colorectal cancer, Dr Baron cautioned against their ...
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