| Carbamoyl phosphate | |
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(Carbamoyloxy)phosphonic acid |
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| Identifiers | |
| CAS number | 590-55-6 |
| PubChem | 278 |
| MeSH | Carbamoyl+phosphate |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | CH2NO5P2- |
| Molar mass | 141.020 g/mol |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Carbamoyl phosphate is an anion of biochemical significance. In land-dwelling animals it is an intermediary metabolite participating in the nitrogen disposal through in the urea cycle and the synthesis of pyrimidines.
It is produced from bicarbonate, ammonia (derived from glutamine), and phosphate (from ATP). The synthesis is catalysed by the enzyme carbamoyl phosphate synthetase, as follows:
- HCO3− + ATP → ADP + HO–C(O)–OPO32− (carboxyl phosphate)
- HO–C(O)–OPO32− + NH3 + OH− → HPO42− + −O–C(O)NH2 + H2O
- −O–C(O)NH2 + ATP → ADP + H2NC(O)OPO32−
See also [edit]
References [edit]
- Nelson, David L. and Michael M. Cox. Lehninger Principles of Biochemistry fourth edition. W. H. Freeman and company New York.
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