Benjamin Wiker obtained his PhD in ethics from Vanderbilt University then went on to teach at a variety of institutions including Marquette University, Saint Mary's University of Minnesota, Thomas Aquinas College, and the Franciscan University of Steubenville. He came to attention in 2002 with the publication of Moral Darwinism: How We Became Hedonists. In this book, Wiker aims to show how Darwinism by its very nature completely undermines the ethical foundations of Christianity, Judaism, and Islam because its materialist cosmology is incompatible with any concept of natural law. Wiker became a member of the Discovery Institute, a think tank supporting this idea, soon after the publication of the book.
His next major book, Architects of the Culture of Death, co-written with veteran Catholic ethicist Donald DeMarco, looks at how the most influential thinkers of the nineteenth and twentieth centuries from Schopenhauer to Peter Singer have undermined the Christian value of "sanctity of life". 2008's 10 Books That Screwed Up the World looks at fifteen important books from The Prince to The Feminine Mystique and aims, following Paul Johnson and E. Michael Jones, to show how the actual lives of these thinkers led to fundamentally distorted views about human nature, morality, and sexuality.
The Darwin Myth is a biography of Charles Darwin which portrays Darwin as a good husband and a kind, charitable person and claims that Darwin was involved in an ideological conspiracy by members of the late Enlightenment which aimed to remove God from science. Wiker uses these claims to support his own belief in a supernaturally guided theistic evolution as an alternative to the naturalist view espoused by Darwin and modern biology.
- Moral Darwinism: How We Became Hedonists (with William A. Dembski), InterVarsity Press, 2002. ISBN 0-8308-2666-1
- The Mystery of the Periodic Table (with Jeanne Bendick), Bethlehem, 2003. ISBN 1-883937-71-X
- Architects of the Culture of Death (with Donald DeMarco), Ignatius, 2004.
- Answering the New Atheism: Dismantling Dawkins' Case Against God (with Scott Hahn), Emmaus Road, 2006. ISBN 1-931018-48-0
- A Meaningful World: How the Arts And Sciences Reveal the Genius of Nature (with Jonathan Witt), InterVarsity PressInterVarsity Press, 2006. ISBN 0-8308-2799-4
- 10 Books That Screwed Up the World (And 5 Others That Didn't Help), Regnery, 2008. ISBN 1-59698-055-9
- The Darwin Myth: The Life and Lies of Charles Darwin, Regnery, 2009. ISBN 1-59698-097-4
- 10 Books Every Conservative Must Read: Plus Four Not to Miss and One Impostor, Regnery, 2010 ISBN 1-59698-604-2
- The Catholic Church & Science: Answering the Questions, Exposing the Myths, TAN Books, 2011. ISBN 978-0-89555-910-4
- Worshipping the State: How Liberalism Became Our State Religion, Regnery, 2013. ISBN 978-1621570295