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Artemotil
Artemotil.svg
Systematic (IUPAC) name
(5aS,6R,8aS,9R,10S,12R,12aR)-10-ethoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy cat.
  • not available
Legal status
?
Routes Intramuscular injection
Pharmacokinetic data
Metabolism Hepatic
Half-life 20 hours
Identifiers
CAS number 75887-54-6 N
ATC code P01BE04
PubChem CID 72416
ChemSpider 16735673 YesY
UNII XGL7GFB9YI YesY
ChEMBL CHEMBL301267 N
Chemical data
Formula C17H28O5 
Mol. mass 312.401 g/mol
 N (what is this?)  (verify)

Artemotil (INN; also known as β-arteether), is a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria cases. It is a semi-synthetic derivative of artemisinin, a natural product of the Chinese plant Artemisia annua. It is currently only used as a second line drug in severe cases of malaria.


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3 videos found

2 news items

 
News-Medical.net
Wed, 10 Sep 2014 05:22:30 -0700

Artemisinin is the intermediate from which the anti-malaria medications artemether, artesunate, artemotil, and dihydroartemisinin are produced. The success of the scientists from Berlin/Potsdam and Magdeburg was achieved from funds of the German Max ...

Medical Xpress

Medical Xpress
Wed, 10 Sep 2014 09:52:30 -0700

Artemisinin is the intermediate from which the anti-malaria medications artemether, artesunate, artemotil, and dihydroartemisinin are produced. The success of the scientists from Berlin/Potsdam and Magdeburg was achieved from funds of the German Max ...
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