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Artemotil
Artemotil.svg
Systematic (IUPAC) name
(5aS,6R,8aS,9R,10S,12R,12aR)-10-ethoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy cat.
  • not available
Legal status
?
Routes Intramuscular injection
Pharmacokinetic data
Metabolism Hepatic
Half-life 20 hours
Identifiers
CAS number 75887-54-6 N
ATC code P01BE04
PubChem CID 3000469
ChemSpider 2272064 N
UNII XGL7GFB9YI YesY
ChEMBL CHEMBL301267 N
Chemical data
Formula C17H28O5 
Mol. mass 312.401 g/mol
 N (what is this?)  (verify)

Artemotil (INN; also known as β-arteether), is a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria cases. It is a semi-synthetic derivative of artemisinin, a natural product of the Chinese plant Artemisia annua. It is currently only used as a second line drug in severe cases of malaria.


Original courtesy of Wikipedia: http://en.wikipedia.org/wiki/Artemotil — Please support Wikipedia.
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2 news items

Medical Xpress

Medical Xpress
Thu, 11 Sep 2014 04:12:19 -0700

Artemisinin is the intermediate from which the anti-malaria medications artemether, artesunate, artemotil, and dihydroartemisinin are produced. The success of the scientists from Berlin/Potsdam and Magdeburg was achieved from funds of the German Max ...
 
OUPblog (blog)
Sun, 23 Nov 2008 00:00:00 -0800

More soluble derivatives, artemether, artether, and artemotil, have been developed in recent years. These medicines, in combination with other antimalarials such as mefloquine, have proved highly effective in treating malaria, particularly the most ...
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