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Aromatic amino acids (AAA)[1] are amino acids that include an aromatic ring.

Examples include:

PhenylalaninetyrosineL-DOPA → (dopamine) → (epinephrine) → (norepinephrine)

Tryptophan5-hydroxytryptophan → (serotonin)

Histidine → (histamine)

Phenylalaninetyrosinethyroxine

See also[edit]

Phenylalanine, histidine, and tryptophan are essential amino acids for animals. Since they are not synthesized in the human body, they must be derived from the diet. Tyrosine is semi-essential; it can be synthesized, but only from phenylalanine. A lack of the enzyme phenylalanine hydroxylase, used in tyrosine synthesis, causes phenylketonuria, and concurrently renders tyrosine an essential amino acid.

All plants and micro-organisms must synthesize their aromatic amino acids through the shikimate pathway in order to make proteins, unlike animals, which obtain them through their diet. Because of the energy intensive nature of amino acid biosynthesis, animals have lost these costly metabolic pathways, since they can obtain aromatic amino acids by ingesting other organisms. Herbicides and antibiotics take advantage of this by inhibiting enzymes involved in aromatic acid synthesis, thereby rendering them toxic to plants and micro-organisms but not animals.

External links[edit]

References[edit]

  1. ^ Logan, Carolynn M.; Rice, M. Katherine (1987). Logan's Medical and Scientific Abbreviations. Philadelphia: J. B. Lippincott Company. p. 3. ISBN 0-397-54589-4. 

Further reading[edit]



Original courtesy of Wikipedia: http://en.wikipedia.org/wiki/Aromatic_amino_acids — Please support Wikipedia.
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4 news items

 
Common Ground.ca
Fri, 31 Oct 2014 18:30:00 -0700

It works with other metalloproteins to “build” several of the building blocks of proteins, the aromatic amino acids. These molecules are also building blocks for a large number of aromatic molecules we call secondary compounds. Glyphosate binds tightly ...

EurekAlert (press release)

EurekAlert (press release)
Sun, 19 Oct 2014 10:03:45 -0700

To add more support to their hypothesis, Lovley's lab genetically altered the structure of the nanowires, removing the aromatic amino acids that provide the delocalized electrons necessary for metallic-like conductivity, winning over more skeptics. But ...

Controlled Environments Magazine

Controlled Environments Magazine
Mon, 20 Oct 2014 11:45:00 -0700

To add more support to their hypothesis, Lovley's lab genetically altered the structure of the nanowires, removing the aromatic amino acids that provide the delocalized electrons necessary for metallic-like conductivity, winning over more skeptics. But ...
 
The Guardian
Sun, 05 Oct 2014 22:01:03 -0700

This week's show looks at the vast community of microbes living inside us - the microbiome. As a new public study examines the effects of diet and lifestyle on these microbial hitchhikers, we consider new research that links childhood obesity to ...
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